Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.45 |
| ▸ | PRKCG | P05129 | 2/20 | 0.45 |
| ▸ | PRKCB | P05771 | 2/20 | 0.45 |
| ▸ | PRKCA | P17252 | 2/20 | 0.45 |
| ▸ | PRKCH | P24723 | 2/20 | 0.45 |
| ▸ | PRKCI | P41743 | 2/20 | 0.45 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.45 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532223 | 0.92 | ALDH1A1 (0.56) | ALDH1A1EPHX1TDP1CHRM2CHRM5 | |
| SCHEMBL13381200 | 0.83 | — | — | |
| SCHEMBL6545523 | 0.83 | ALDH1A1 (1.00) | ALDH1A1EPHX1TDP1TSHRPRKD3 | |
| SCHEMBL284277 | 0.83 | ALDH1A1 (1.00) | ALDH1A1EPHX1TDP1TSHRPRKD3 | |
| SCHEMBL2847668 | 0.83 | ALDH1A1 (1.00) | ALDH1A1EPHX1TDP1TSHRPRKD3 | |
| SCHEMBL23495987 | 0.83 | ALDH1A1 (1.00) | ALDH1A1EPHX1TDP1TSHRPRKD3 | |
| SCHEMBL283556 | 0.83 | ALDH1A1 (1.00) | ALDH1A1EPHX1TDP1TSHRPRKD3 | |
| SCHEMBL11148662 | 0.83 | ALDH1A1 (1.00) | ALDH1A1EPHX1TDP1TSHRPRKD3 | |
| SCHEMBL10787246 | 0.83 | ALDH1A1 (1.00) | ALDH1A1EPHX1TDP1TSHRPRKD3 | |
| SCHEMBL7353212 | 0.83 | ALDH1A1 (1.00) | ALDH1A1EPHX1TDP1TSHRPRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |
| US-4435315-A | COSMETICS, DETERGENTS | HENKEL KOMMANDITGESELLSCHAFT AUF ATKIEN (DE) | 1984-03-06 | — | — | US | disclosed |
| EP-0033928-A2 | Use of alkyl-substituted 1,3-dioxolanes as perfumes, and perfume compositions containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1981-08-19 | — | — | EP | disclosed |