Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.45 |
| ▸ | PRKCG | P05129 | 2/20 | 0.45 |
| ▸ | PRKCB | P05771 | 2/20 | 0.45 |
| ▸ | PRKCA | P17252 | 2/20 | 0.45 |
| ▸ | PRKCH | P24723 | 2/20 | 0.45 |
| ▸ | PRKCI | P41743 | 2/20 | 0.45 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.45 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.45 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.45 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12977806 | 1.00 | ALDH1A1 (1.00) | ALDH1A1EPHX1TDP1CYP1A2SPHK1 | |
| SCHEMBL284277 | 1.00 | ALDH1A1 (1.00) | ALDH1A1EPHX1TDP1CYP1A2SPHK1 | |
| SCHEMBL7353212 | 1.00 | ALDH1A1 (1.00) | ALDH1A1EPHX1TDP1CYP1A2SPHK1 | |
| SCHEMBL11148662 | 1.00 | ALDH1A1 (1.00) | ALDH1A1EPHX1TDP1CYP1A2SPHK1 | |
| SCHEMBL283556 | 1.00 | ALDH1A1 (1.00) | ALDH1A1EPHX1TDP1CYP1A2SPHK1 | |
| SCHEMBL23495987 | 1.00 | ALDH1A1 (1.00) | ALDH1A1EPHX1TDP1CYP1A2SPHK1 | |
| SCHEMBL9622281 | 1.00 | ALDH1A1 (1.00) | ALDH1A1EPHX1TDP1CYP1A2SPHK1 | |
| SCHEMBL5313598 | 1.00 | ALDH1A1 (1.00) | ALDH1A1EPHX1TDP1CYP1A2SPHK1 | |
| SCHEMBL2847668 | 1.00 | ALDH1A1 (1.00) | ALDH1A1EPHX1TDP1CYP1A2SPHK1 | |
| SCHEMBL10787246 | 1.00 | ALDH1A1 (1.00) | ALDH1A1EPHX1TDP1CYP1A2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11433144-B2 | Biodegradable lipids for delivery of nucleic acids | TRANSLATE BIO, INC. (US) | 2022-09-06 | — | — | US | disclosed |
| EP-3587409-B1 | BIODEGRADABLE LIPIDS FOR DELIVERY OF NUCLEIC ACIDS | TRANSLATE BIO INC (US) | 2022-06-01 | — | — | EP | disclosed |
| US-20210369866-A1 | BIODEGRADABLE LIPIDS FOR DELIVERY OF NUCLEIC ACIDS | TRANSLATE BIO, INC. | 2021-12-02 | — | — | US | disclosed |
| US-10912844-B2 | Biodegradable lipids for delivery of nucleic acids | TRANSLATE BIO, INC. (US) | 2021-02-09 | — | — | US | disclosed |
| EP-3341981-B1 | FORMULATION OF AN ORGANIC FUNCTIONAL MATERIAL COMPRISING AN EPOXY GROUP CONTAINING SOLVENT | MERCK PATENT GMBH (DE) | 2020-08-19 | — | — | EP | disclosed |
| US-20200222558-A1 | BIODEGRADABLE LIPIDS FOR DELIVERY OF NUCLEIC ACIDS | RANA THERAPEUTICS, INC. | 2020-07-16 | — | — | US | disclosed |
| EP-3148552-B1 | BIODEGRADABLE LIPIDS FOR DELIVERY OF NUCLEIC ACIDS | TRANSLATE BIO INC (US) | 2019-07-31 | — | — | EP | disclosed |
| US-10293057-B2 | Biodegradable lipids for delivery of nucleic acids | TRANSLATE BIO, INC. (US) | 2019-05-21 | — | — | US | disclosed |
| US-10286083-B2 | Biodegradable lipids for delivery of nucleic acids | TRANSLATE BIO, INC. (US) | 2019-05-14 | — | — | US | disclosed |
| US-10286082-B2 | Biodegradable lipids for delivery of nucleic acids | TRANSLATE BIO, INC. (US) | 2019-05-14 | — | — | US | disclosed |
| US-20110293703-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-12-01 | — | — | US | disclosed |
| US-20110293703-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-12-01 | — | — | US | disclosed |
| US-20100331234-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-12-30 | — | — | US | disclosed |
| US-20100331234-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-12-30 | — | — | US | disclosed |
| WO-2010129709-A1 | LIPID COMPOSITIONS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010053572-A2 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-05-14 | — | — | WO | disclosed |
| US-7220870-B2 | Hydrolytic kinetic resolution of cyclic substrates | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2007-05-22 | — | — | US | disclosed |
| US-20040082799-A1 | Process for producing substituted epoxides | ISIS INNOVATION LIMITED (GB) | 2004-04-29 | — | — | US | disclosed |
| EP-1377561-A1 | PROCESS FOR PRODUCING SUBSTITUTED EPOXIDES | ISIS INNOVATION LIMITED (GB) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002053549-A1 | PROCESS FOR PRODUCING SUBSTITUTED EPOXIDES | ISIS INNOVATION LIMITED (GB) | 2002-07-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210369866-A1 | BIODEGRADABLE LIPIDS FOR DELIVERY OF NUCLEIC ACIDS | LIPA, SLC67A1, SREBF1 | ALDH1A1 2846/4885EPHX1 3451/4885TDP1 1213/4885 |
| US-10286083-B2 | Biodegradable lipids for delivery of nucleic acids | LIPA, SLC67A1, SREBF1 | ALDH1A1 2846/4885EPHX1 3451/4885TDP1 1213/4885 |
| US-10293057-B2 | Biodegradable lipids for delivery of nucleic acids | LIPA, SLC67A1, SREBF1 | ALDH1A1 2846/4885EPHX1 3451/4885TDP1 1213/4885 |
| US-11433144-B2 | Biodegradable lipids for delivery of nucleic acids | LIPA, SLC67A1, SREBF1 | ALDH1A1 2846/4885EPHX1 3451/4885TDP1 1213/4885 |
| US-20110293703-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | PHOSPHO1, PNMT, AASDHPPT | ALDH1A1 568/4885EPHX1 58/4885TDP1 1703/4885 |
| US-10912844-B2 | Biodegradable lipids for delivery of nucleic acids | LIPA, SLC67A1, SREBF1 | ALDH1A1 2846/4885EPHX1 3451/4885TDP1 1213/4885 |
| US-20040082799-A1 | Process for producing substituted epoxides | RER1, OXER1, EPHX2 | ALDH1A1 1017/4885EPHX1 9/4885TDP1 4311/4885 |
| US-10286082-B2 | Biodegradable lipids for delivery of nucleic acids | LIPA, SLC67A1, SREBF1 | ALDH1A1 2846/4885EPHX1 3451/4885TDP1 1213/4885 |
| US-20200222558-A1 | BIODEGRADABLE LIPIDS FOR DELIVERY OF NUCLEIC ACIDS | LIPA, SLC67A1, SREBF1 | ALDH1A1 2846/4885EPHX1 3451/4885TDP1 1213/4885 |
| US-20100331234-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | PHOSPHO1, PNMT, AASDHPPT | ALDH1A1 568/4885EPHX1 58/4885TDP1 1703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.