SCHEMBL9113350

SCHEMBL9113350

Cn1ccnc1C(C#N)C#N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.44
LPO P22079 1/20 0.40
CYP2D6 P10635 1/20 0.39
GAA P10253 2/20 0.38
MAPT P10636 2/20 0.38
ALOX15 P16050 2/20 0.38
HSD17B10 Q99714 2/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
PKM P14618 1/20 0.38
TSHR P16473 1/20 0.38
ALOX12 P18054 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PGR P06401 1/20 0.36
KMT2A Q03164 3/20 0.34
MEN1 O00255 1/20 0.33
FGB P02675 1/20 0.33
TNNI3 P19429 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL372623 0.82 KDM4E (0.43) KDM4ELPOCYP2D6GAAMAPT
Hydrochloric Acid SCHEMBL28434530 0.80 KDM4E (0.42) KDM4ELPOCYP2D6GAAMAPT
SCHEMBL15611853 0.77 L3MBTL1 (0.44) KDM4ELPOCYP2D6GAAMAPT
SCHEMBL28434485 0.76 KDM4E (0.39) KDM4ELPOCYP2D6GAAMAPT
SCHEMBL21086408 0.76 KDM4E (0.39) KDM4ELPOCYP2D6GAAMAPT
Hydrochloric Acid SCHEMBL28982043 0.76 L3MBTL1 (0.43) KDM4ELPOCYP2D6GAAMAPT
SCHEMBL4065140 0.75 KDM4E (0.52) KDM4ELPOCYP2D6GAAMAPT
SCHEMBL28072046 0.73 KDM4E (0.59) KDM4ECYP2D6GAAMAPTALOX15
Thiocyanic Acid SCHEMBL27793112 0.73 KDM4E (0.47) KDM4ELPOCYP2D6GAAMAPT
SCHEMBL48851 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995011319-A1 GOLD LIXIVIATION USING NITROGEN AND SULFUR HETEROCYCLIC AROMATIC COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-04-27 WO disclosed