Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | LPO | P22079 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | FGB | P02675 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15611853 | 0.84 | L3MBTL1 (0.44) | KDM4EL3MBTL1CYP2D6LPOGAA | |
| Hydrochloric Acid SCHEMBL28982043 | 0.83 | L3MBTL1 (0.43) | KDM4EL3MBTL1CYP2D6LPOGAA | |
| SCHEMBL28982056 | 0.79 | L3MBTL1 (0.40) | KDM4EL3MBTL1CYP2D6LPOGAA | |
| Acetic Acid SCHEMBL28603086 | 0.76 | L3MBTL1 (0.42) | KDM4EL3MBTL1CYP2D6GAAMAPT | |
| SCHEMBL9113350 | 0.76 | KDM4E (0.44) | KDM4EL3MBTL1CYP2D6LPOGAA | |
| SCHEMBL2474436 | 0.74 | KDM4E (0.43) | KDM4EL3MBTL1CYP2D6LPOGAA | |
| Nitric Acid SCHEMBL28891095 | 0.74 | L3MBTL1 (0.40) | KDM4EL3MBTL1CYP2D6GAAMAPT | |
| SCHEMBL372623 | 0.74 | KDM4E (0.43) | KDM4EL3MBTL1CYP2D6LPOGAA | |
| SCHEMBL17385605 | 0.73 | KDM4E (0.50) | KDM4EL3MBTL1CYP2D6LPOGAA | |
| Hydrochloric Acid SCHEMBL28434530 | 0.73 | KDM4E (0.42) | KDM4EL3MBTL1CYP2D6LPOGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2962687-B1 | TAU AGGREGATION INHIBITOR | THE DOSHISHA (JP) | 2019-06-05 | — | — | EP | disclosed |