Dimethyl Sulfoxide

Dimethyl Sulfoxide

SCHEMBL9113663

C[S+](C)[O-].C[S+](C)[O-].ClCC(Cl)Cl

nearest known ligand 0.41

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Known targets — ChEMBL curated mechanism

MAP2K1MAP2K2

The experimentally established mechanism targets of Dimethyl Sulfoxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethyl Sulfoxide SCHEMBL590616 0.76
Dimethyl Sulfoxide SCHEMBL383457 0.76
Dimethyl Sulfoxide SCHEMBL6267761 0.76 LMNA (0.40) ALDH1A1TSHR
Dimethyl Sulfoxide SCHEMBL1665533 0.76 ALDH1A1 (0.40) ALDH1A1
SCHEMBL16435 0.76
Dimethyl Sulfoxide SCHEMBL17332152 0.72
Dimethyl Sulfoxide SCHEMBL3819555 0.72 ALDH1A1 (0.55) ALDH1A1TSHR
Dimethyl Sulfoxide SCHEMBL4234311 0.72
Methyl Alcohol SCHEMBL1871619 0.72
Ethyl Chloride SCHEMBL11708562 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0628024-A4 SYNTHESIS OF IOVERSOL USING A MINIMAL EXCESS OF ACETOXYACETYLCHLORIDE. MALLINCKRODT MEDICAL INC (US) 1995-03-22 EP disclosed
EP-0628024-A1 SYNTHESIS OF IOVERSOL USING A MINIMAL EXCESS OF ACETOXYACETYLCHLORIDE MALLINCKRODT MEDICAL, INC. (US) 1994-12-14 EP disclosed
WO-1993016981-A1 SYNTHESIS OF IOVERSOL USING A MINIMAL EXCESS OF ACETOXYACETYLCHLORIDE MALLINCKRODT MEDICAL, INC. (US) 1993-09-02 WO disclosed