Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | FADS1 | O60427 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112011 | 0.89 | HTR2C (0.36) | HTR2CFADS1TRPA1 | |
| SCHEMBL9114591 | 0.83 | HTR2C (0.34) | HTR2CFADS1TRPA1 | |
| SCHEMBL9112969 | 0.80 | HTR2C (0.34) | HTR2CFADS1TRPA1 | |
| SCHEMBL9114098 | 0.75 | TRPA1 (0.33) | HTR2CFADS1TRPA1 | |
| SCHEMBL9110040 | 0.73 | HTR2C (0.36) | HTR2CFADS1TRPA1 | |
| SCHEMBL9109755 | 0.70 | HTR2C (0.33) | HTR2CFADS1TRPA1 | |
| SCHEMBL3803166 | 0.70 | HTR2C (0.40) | HTR2CFADS1TRPA1KCNA3 | |
| SCHEMBL31426315 | 0.70 | PDE3B (0.42) | HTR2CFADS1TRPA1KCNA3 | |
| SCHEMBL8371407 | 0.70 | HTR2C (0.42) | HTR2CFADS1TRPA1 | |
| SCHEMBL9113007 | 0.69 | TRPA1 (0.33) | HTR2CFADS1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |