Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 12/20 | 0.52 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029049 | 0.88 | NISCH (0.55) | NISCHHTR1DADRA1APRMT1 | |
| SCHEMBL9112606 | 0.80 | NISCH (0.51) | NISCHHTR1DADRA1APRMT1 | |
| SCHEMBL9029139 | 0.79 | NISCH (0.54) | NISCHPRMT1 | |
| SCHEMBL13204584 | 0.79 | NISCH (0.54) | NISCHPRMT1 | |
| SCHEMBL548359 | 0.78 | NISCH (0.52) | NISCHPRMT1 | |
| SCHEMBL9029931 | 0.77 | NISCH (0.51) | NISCHPRMT1 | |
| SCHEMBL548343 | 0.76 | NISCH (0.50) | NISCHPRMT1 | |
| SCHEMBL8677423 | 0.76 | NISCH (0.50) | NISCHPRMT1 | |
| SCHEMBL549218 | 0.76 | TOP2A (0.56) | NISCHPRMT1 | |
| SCHEMBL14599548 | 0.75 | PRMT1 (0.49) | NISCHPRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995008540-A1 | BIS(AMIDINOBENZIMIDAZOLYL)ALKANES AS ANTIVIRAL AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-03-30 | — | — | WO | disclosed |