Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.46 |
| ▸ | CCR8 | P51685 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2424951 | 0.81 | CYP1A2 (0.47) | SMN1; SMN2OPRD1KDM4ELMNACYP1A2 | |
| SCHEMBL30989133 | 0.79 | KDM4E (0.72) | SMN1; SMN2KDM4ELMNACYP1A2CCR1 | |
| SCHEMBL30989132 | 0.79 | KDM4E (0.72) | SMN1; SMN2KDM4ELMNACYP1A2CCR1 | |
| SCHEMBL1566968 | 0.79 | KDM4E (0.72) | SMN1; SMN2KDM4ELMNACYP1A2CCR1 | |
| SCHEMBL4298850 | 0.79 | TAAR1 (0.48) | OPRD1KDM4ELMNACYP1A2CCR1 | |
| SCHEMBL2715731 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL750061 | 0.78 | KDM4E (0.62) | SMN1; SMN2KDM4ELMNACYP1A2CCR1 | |
| SCHEMBL29730352 | 0.78 | KDM4E (0.62) | SMN1; SMN2KDM4ELMNACYP1A2CCR1 | |
| SCHEMBL5427655 | 0.77 | LMNA (0.53) | OPRD1KDM4ELMNACYP1A2CCR1 | |
| SCHEMBL8925746 | 0.77 | CA1 (0.64) | SMN1; SMN2LMNACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5453509-A | Functionalization of acyl pyridinium salts | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1995-09-26 | — | — | US | disclosed |
| WO-1995010505-A1 | FUNCTIONALIZATION OF ACYL PYRIDINIUM SALTS | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1995-04-20 | — | — | WO | disclosed |