SCHEMBL750061

SCHEMBL750061

c1ccc(-c2ccc(-c3ccccn3)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.62
LMNA P02545 5/20 0.62
CYP1A2 P05177 2/20 0.62
CCR1 P32246 2/20 0.62
CCR5 P51681 2/20 0.62
CCR8 P51685 2/20 0.62
POLB P06746 1/20 0.62
METAP1 P53582 1/20 0.62
BLM P54132 1/20 0.62
HIF1A Q16665 1/20 0.62
DOHH Q9BU89 1/20 0.62
P4HTM Q9NXG6 1/20 0.62
CYP2A6 P11509 1/20 0.59
RAB9A P51151 7/20 0.56
TP53 P04637 5/20 0.56
SMN1; SMN2 Q16637 5/20 0.56
PKM P14618 3/20 0.56
MAPT P10636 3/20 0.56
ALDH1A1 P00352 2/20 0.56
HPGD P15428 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29730352 1.00 KDM4E (0.62) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL27635174 0.98 KDM4E (0.59) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL21173034 0.95 KDM4E (0.62) KDM4ELMNACYP1A2CCR1CCR5
Benzene SCHEMBL29224585 0.95 KDM4E (0.68) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL29360780 0.95 KDM4E (0.68) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL13458076 0.95 KDM4E (0.68) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL28062312 0.95 KDM4E (0.68) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL29984274 0.95 KDM4E (0.68) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL35754 0.95 KDM4E (0.68) KDM4ELMNACYP1A2CCR1CCR5
Bromide SCHEMBL15901958 0.92 KDM4E (0.65) KDM4ELMNACYP1A2CCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111793095-A Preparation method and application of cyclometalated platinum complex 大连理工大学 2020-10-20 CN claimed
CN-111187301-A Preparation method and application of aggregation-induced emission iridium complex 大连理工大学 2020-05-22 CN claimed
CN-104628787-A Green-emission iridium phosphors complex and preparation method thereof KUNMING INST PRECIOUS METALS 2015-05-20 CN claimed
CN-101179112-B Organic light emitting diode including organic layer comprising organic metal complex SAMSUNG SDI CO LTD 2010-12-15 CN claimed
US-7727690-B2 Iridium complex, carbazole derivatives and copolymer having the same GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2010-06-01 US claimed
EP-1923385-B1 Iridium complex, carbazole derivatives and copolymer having the same KWANGJU INST SCI & TECH (KR) 2009-05-27 EP claimed
US-20080177084-A1 IRIDIUM COMPLEX, CARBAZOLE DERIVATIVES AND COPOLYMER HAVING THE SAME GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-07-24 US claimed
CN-101179112-A Organic light emitting diode including organic layer comprising organic metal complex SAMSUNG SDI CO LTD (KR) 2008-05-14 CN claimed
US-12127470-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-10-22 US disclosed
EP-4223854-A2 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2023-08-09 EP disclosed
EP-4223854-A2 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2023-08-09 EP disclosed
EP-3399005-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2023-05-31 EP disclosed
US-20230053347-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-02-23 US disclosed
US-20230053347-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-02-23 US disclosed
US-4377585-A Use of 4-[4(or 3)-aminophenyl]pyridines as cardiotonic agents STERLING DRUG INC. (US) 1983-03-22 US disclosed
US-4376775-A N-[4-(4-Pyridinyl)phenyl]ureas and their cardiotonic use STERLING DRUG INC. (US) 1983-03-15 US disclosed
US-4366319-A Process for preparing 5-(pyridinyl)benzoxazol-2(3H)-ones STERLING DRUG INC. (US) 1982-12-28 US disclosed
US-4317827-A 4-[4(or 3)-Acylaminophenyl]pyridines and their use as cardiotonics STERLING DRUG INC. (US) 1982-03-02 US disclosed
US-4310531-A 5-(Pyridinyl)-benzoxazol-2(3H)-ones and their use as cardiotonics STERLING DRUG INC. (US) 1982-01-12 US disclosed
US-4297363-A 2-Amino-3(4 or 5)-(pyridinyl)phenols and their use as cardiotonics STERLING DRUG INC. (US) 1981-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12127470-B2 Organic electroluminescent materials and devices SOD1, CLTB, L1CAM KDM4E 3163/4885LMNA 87/4885CYP1A2 1949/4885
US-20080177084-A1 IRIDIUM COMPLEX, CARBAZOLE DERIVATIVES AND COPOLYMER HAVING THE SAME INTS9, HIRIP3, HELZ KDM4E 4229/4885LMNA 4851/4885CYP1A2 574/4885
US-20230053347-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, CLTB, L1CAM KDM4E 3163/4885LMNA 87/4885CYP1A2 1949/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.