Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 6/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | SUZ12 | Q15022 | 3/20 | 0.32 |
| ▸ | EZH2 | Q15910 | 3/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | FADS1 | O60427 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4563794 | 0.81 | EED (0.43) | EEDMTNR1AMTNR1BKCNA3MAOA | |
| SCHEMBL2095736 | 0.78 | EED (0.46) | EEDMTNR1AMTNR1BKCNA3MAOA | |
| SCHEMBL446625 | 0.77 | EED (0.43) | EEDMTNR1AMTNR1BKCNA3MAOA | |
| SCHEMBL2094789 | 0.75 | EED (0.44) | EEDMTNR1AMTNR1BKCNA3MAOA | |
| SCHEMBL9111374 | 0.75 | KCNA3 (0.36) | EEDKCNA3MAOAMAOBFTO | |
| SCHEMBL8835248 | 0.72 | EED (0.42) | EEDMTNR1AMTNR1BKCNA3MAOA | |
| SCHEMBL3794946 | 0.71 | MTNR1A (0.51) | EEDMTNR1AMTNR1BKCNA3MAOA | |
| SCHEMBL957263 | 0.71 | EED (0.46) | EEDMTNR1AMTNR1BKCNA3MAOA | |
| SCHEMBL506855 | 0.71 | EED (0.46) | EEDMTNR1AMTNR1BKCNA3MAOA | |
| SCHEMBL5357479 | 0.71 | MAOB (0.47) | EEDMTNR1AMTNR1BKCNA3MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |