Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.38 |
| ▸ | AHCY | P23526 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.37 |
| ▸ | ADA | P00813 | 1/20 | 0.37 |
| ▸ | PI4KA | P42356 | 3/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.36 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9114924 | 1.00 | ADORA2A (0.38) | ADORA2AADORA2BAHCYADORA1ADORA3 | |
| SCHEMBL9115023 | 0.86 | ADORA2A (0.56) | ADORA2AADORA2BAHCYADORA1ADORA3 | |
| SCHEMBL9115171 | 0.86 | FGFR1 (0.38) | ADORA2AADORA2BAHCYADORA1ADORA3 | |
| SCHEMBL9115027 | 0.86 | ADORA2A (0.56) | ADORA2AADORA2BAHCYADORA1ADORA3 | |
| SCHEMBL9115181 | 0.86 | FGFR1 (0.38) | ADORA2AADORA2BAHCYADORA1ADORA3 | |
| SCHEMBL9113289 | 0.83 | YTHDC1 (0.59) | ADORA2AAHCYADORA1ADORA3YTHDC1 | |
| SCHEMBL9114712 | 0.74 | AHCY (0.54) | ADORA2AADORA2BAHCYADORA3 | |
| SCHEMBL9114703 | 0.74 | AHCY (0.54) | ADORA2AADORA2BAHCYADORA3 | |
| SCHEMBL9115355 | 0.73 | PDE4D (0.54) | ADORA2AADORA1ADORA3 | |
| SCHEMBL9115366 | 0.73 | PDE4D (0.54) | ADORA2AADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5478928-A | Useful as antiviral agents in the treatment and prevention of AIDS | SOUTHERN RESEARCH INSTITUTE (US) | 1995-12-26 | — | — | US | claimed |
| WO-1995011685-A1 | 2',3'-DIDEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1995-05-04 | — | — | WO | claimed |
| US-5478928-A | Useful as antiviral agents in the treatment and prevention of AIDS | SOUTHERN RESEARCH INSTITUTE (US) | 1995-12-26 | — | — | US | disclosed |
| WO-1995011685-A1 | 2',3'-DIDEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1995-05-04 | — | — | WO | disclosed |
| US-5128458-A | 2',3'-dideoxy-4'-thioribonucleosides as antiviral agents | SOUTHERN RESEARCH INSTITUTE (US) | 1992-07-07 | — | — | US | disclosed |
| WO-1991016333-A1 | 2',3'-DIDEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1991-10-31 | — | — | WO | disclosed |