Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13799417 | 0.78 | HRH3 (0.54) | TDP1HRH3GABRA1GABRB2ALDH1A1 | |
| SCHEMBL6832785 | 0.74 | CA1 (0.50) | TDP1ALDH1A1GAALMNA | |
| SCHEMBL8978552 | 0.73 | TDP1 (0.41) | TDP1HRH3GABRA1GABRB2ALDH1A1 | |
| SCHEMBL15803238 | 0.72 | TDP1 (0.53) | TDP1ALDH1A1GAASMN1; SMN2RAB9A | |
| SCHEMBL8978557 | 0.70 | TDP1 (0.63) | TDP1GABRA1GABRB2ALDH1A1GAA | |
| SCHEMBL20482328 | 0.69 | TDP1 (0.54) | TDP1ALDH1A1GAASMN1; SMN2RAB9A | |
| SCHEMBL3637464 | 0.69 | TDP1 (0.50) | TDP1ALDH1A1GAASMN1; SMN2RAB9A | |
| SCHEMBL15906494 | 0.69 | KDM4E (0.45) | TDP1ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL13799416 | 0.69 | ALDH1A1 (0.49) | TDP1HRH3ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL5174129 | 0.68 | PBRM1 (0.54) | TDP1ALDH1A1GAARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995016215-A1 | NOVEL SUBSTITUTED NAPHTHOPYRANS | PPG INDUSTRIES, INC. (US) | 1995-06-15 | — | — | WO | disclosed |