Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 12/20 | 0.70 |
| ▸ | IDO2 | Q6ZQW0 | 9/20 | 0.70 |
| ▸ | IDO1 | P14902 | 14/20 | 0.69 |
| ▸ | APAF1 | O14727 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | MITF | O75030 | 1/20 | 0.69 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.67 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.67 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26614168 | 0.85 | APAF1 (0.67) | TDO2IDO2IDO1APAF1NPC1 | |
| SCHEMBL30639101 | 0.85 | APAF1 (0.67) | TDO2IDO2IDO1APAF1NPC1 | |
| SCHEMBL9100562 | 0.85 | TDO2 (0.64) | TDO2IDO2IDO1APAF1NPC1 | |
| SCHEMBL11904068 | 0.84 | IDO1 (0.70) | TDO2IDO2IDO1APAF1NPC1 | |
| SCHEMBL9105381 | 0.83 | TDO2 (0.58) | TDO2IDO2IDO1APAF1NPC1 | |
| SCHEMBL9103006 | 0.83 | TDO2 (1.00) | TDO2IDO2IDO1APAF1NPC1 | |
| SCHEMBL9115231 | 0.82 | TDO2 (1.00) | TDO2IDO2IDO1APAF1NPC1 | |
| SCHEMBL9222306 | 0.82 | IDO1 (1.00) | TDO2IDO2IDO1APAF1NPC1 | |
| SCHEMBL9099548 | 0.82 | TDO2 (0.74) | TDO2IDO2IDO1APAF1NPC1 | |
| SCHEMBL31680506 | 0.82 | TDO2 (1.00) | TDO2IDO2IDO1APAF1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5441955-A | Tuberculosis | PATHOGENESIS CORPORATION (US) | 1995-08-15 | — | — | US | disclosed |
| WO-1995013807-A1 | INDOLO[2,1-b]QUINAZOLINE-6,12-DIONE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | PATHOGENESIS CORPORATION (US) | 1995-05-26 | — | — | WO | disclosed |