Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 7/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | GPR6 | P46095 | 1/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL911501 | 1.00 | OPRK1 (0.54) | OPRK1SLC6A3SLC6A2SLC6A4CHRM2 | |
| SCHEMBL911692 | 0.88 | SLC6A2 (0.59) | OPRK1SLC6A3SLC6A2SLC6A4CHRM2 | |
| SCHEMBL911693 | 0.88 | SLC6A2 (0.59) | OPRK1SLC6A3SLC6A2SLC6A4CHRM2 | |
| Trifluoroacetic Acid SCHEMBL911957 | 0.85 | OPRK1 (0.57) | OPRK1SLC6A3SLC6A2SLC6A4KCNH2 | |
| Trifluoroacetic Acid SCHEMBL911959 | 0.85 | OPRK1 (0.57) | OPRK1SLC6A3SLC6A2SLC6A4KCNH2 | |
| SCHEMBL911503 | 0.75 | OPRK1 (0.37) | OPRK1SLC6A3SLC6A2SLC6A4KCNH2 | |
| SCHEMBL911193 | 0.75 | SLC6A2 (0.87) | OPRK1SLC6A3SLC6A2SLC6A4CHRM2 | |
| SCHEMBL911194 | 0.75 | SLC6A2 (0.87) | OPRK1SLC6A3SLC6A2SLC6A4CHRM2 | |
| Trifluoroacetic Acid SCHEMBL15476928 | 0.74 | SLC6A3 (0.57) | OPRK1SLC6A3SLC6A2SLC6A4CHRM2 | |
| Trifluoroacetic Acid SCHEMBL15476929 | 0.74 | SLC6A3 (0.57) | OPRK1SLC6A3SLC6A2SLC6A4CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7868017-B2 | 9-azabicyclo[3.3.1]nonane derivatives | N.V. ORGANON (NL) | 2011-01-11 | — | — | US | disclosed |
| EP-1934212-A1 | 9-AZABICYCLO [3 . 3 . 1]NONANE DERIVATIVES AS MONOAMINE REUPTAKE INHIBITORS | N.V. Organon (NL) | 2008-06-25 | — | — | EP | disclosed |
| US-20070112019-A1 | 9-Azabicyclo[3.3.1]nonane derivatives | N.V. ORGANON (NL) | 2007-05-17 | — | — | US | disclosed |
| WO-2007039563-A1 | 9-AZABICYCLO [3 . 3 . 1] NONANE DERIVATIVES AS MONOAMINE REUPTAKE INHIBITORS | N.V. ORGANON (NL) | 2007-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112019-A1 | 9-Azabicyclo[3.3.1]nonane derivatives | AZI2, TPMT, TET3 | OPRK1 3261/4885SLC6A3 339/4885SLC6A2 1059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.