Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5422827 | 0.82 | KCNA5 (0.48) | POLBMAPK1NPSR1ALDH1A1NPC1 | |
| SCHEMBL1562840 | 0.81 | ACE (0.41) | ALDH1A1 | |
| SCHEMBL27459998 | 0.81 | ACE (0.41) | ALDH1A1 | |
| SCHEMBL9639124 | 0.80 | POLB (0.39) | POLBMAPK1NPSR1ALDH1A1NPC1 | |
| SCHEMBL18261157 | 0.80 | SLC7A5 (0.61) | NPSR1ALPIPKMPTGS1XIAP | |
| SCHEMBL3834508 | 0.80 | LTA4H (0.38) | POLBMAPK1NPSR1ALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL10509889 | 0.80 | ACE (0.40) | ALDH1A1 | |
| SCHEMBL31527967 | 0.80 | ALDH1A1 (0.56) | ALDH1A1HTTKMT2ACYP2C19 | |
| SCHEMBL6690977 | 0.77 | ALDH1A1 (0.43) | POLBMAPK1ALDH1A1GABBR2GABBR1 | |
| SCHEMBL8850414 | 0.77 | CYP1A2 (0.39) | POLBMAPK1ALDH1A1KMT2AGABBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995017828-A1 | CHEWING GUM CONTAINING BETA GLUCAN-STABILIZED ASPARTAME | WM. WRIGLEY JR. COMPANY (US) | 1995-07-06 | — | — | WO | disclosed |
| US-5175009-A | Calcium carbonate free; mixing food acids to control pH below 5; consists of water soluble bulk portion, base portion, flavoring agent and aspartame | WM. WRIGLEY JR. COMPANY (US) | 1992-12-29 | — | — | US | disclosed |
| US-4508912-A | UNING METAL OXIDE, HYDROXIDE, ACID OR ACID SALT, OR ORGANOBASIC COMPOUND CATALYST | AJINOMOTO COMPANY, INCORPORATED (JP) | 1985-04-02 | — | — | US | disclosed |