Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9116393 | 1.00 | HMGCR (0.59) | HMGCRHTTKMT2AMEN1PAK1 | |
| SCHEMBL9117235 | 1.00 | HMGCR (0.59) | HMGCRHTTKMT2AMEN1PAK1 | |
| SCHEMBL1441269 | 1.00 | HMGCR (0.59) | HMGCRHTTKMT2AMEN1PAK1 | |
| SCHEMBL9116037 | 0.98 | HMGCR (0.61) | HMGCRHTTKMT2AMEN1PAK1 | |
| SCHEMBL1441802 | 0.88 | KMT2A (0.49) | HMGCRKMT2AMEN1HDAC8HDAC1 | |
| SCHEMBL27200200 | 0.85 | CTNNB1 (0.43) | HMGCRHTTKMT2AHDAC8HDAC1 | |
| SCHEMBL9506703 | 0.84 | HDAC8 (0.42) | HMGCRHTTKMT2AHDAC8HDAC1 | |
| SCHEMBL9972449 | 0.80 | HTT (0.44) | HTTKMT2AMEN1HPGDRECQL | |
| SCHEMBL1442018 | 0.79 | NPC1 (0.56) | HTTKMT2AMEN1HDAC8HDAC1 | |
| SCHEMBL9116063 | 0.79 | NPC1 (0.57) | HTTKMT2AMEN1HDAC8HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995025731-A1 | NOVEL 3-(φ-(4-BENZOYLPIPERIDINO)ALKYL)-4H-BENZOPYRAN-4-ONES, PREPARATION AND THERAPEUTICAL USE THEREOF | PIERRE FABRE MEDICAMENT (FR) | 1995-09-28 | — | — | WO | disclosed |