Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1442749 | 1.00 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL9117437 | 1.00 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL9117394 | 1.00 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL9117204 | 0.99 | NPC1 (0.58) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL1442018 | 0.89 | NPC1 (0.56) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL9114685 | 0.87 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL14261562 | 0.87 | MEN1 (0.55) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL7267209 | 0.86 | MAPT (0.55) | MEN1KMT2AKDM4ETP53MAPT | |
| SCHEMBL8537739 | 0.83 | RAB9A (0.56) | NPC1RAB9AMEN1KMT2ATP53 | |
| SCHEMBL9116412 | 0.82 | NPC1 (0.56) | NPC1RAB9AMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995025731-A1 | NOVEL 3-(φ-(4-BENZOYLPIPERIDINO)ALKYL)-4H-BENZOPYRAN-4-ONES, PREPARATION AND THERAPEUTICAL USE THEREOF | PIERRE FABRE MEDICAMENT (FR) | 1995-09-28 | — | — | WO | disclosed |