Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | LAP3 | P28838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL9115149 | 0.92 | LAP3 (0.42) | LAP3 | |
| SCHEMBL9245727 | 0.76 | SGPL1 (0.44) | LAP3 | |
| SCHEMBL28235625 | 0.74 | CYP2D6 (0.46) | CYP2D6SPHK1LMNAGMNNPOLB | |
| SCHEMBL5671085 | 0.73 | SPHK1 (0.50) | CYP2D6SPHK1LMNAGMNNPOLB | |
| SCHEMBL10944404 | 0.73 | SPHK1 (0.50) | CYP2D6SPHK1LMNAGMNNPOLB | |
| SCHEMBL10944400 | 0.73 | SPHK1 (0.50) | CYP2D6SPHK1LMNAGMNNPOLB | |
| SCHEMBL4008504 | 0.73 | SPHK1 (0.50) | CYP2D6SPHK1LMNAGMNNPOLB | |
| SCHEMBL8499519 | 0.71 | FFAR4 (0.46) | CYP2D6SPHK1LMNAGMNNPOLB | |
| SCHEMBL23706318 | 0.71 | LMNA (0.48) | CYP2D6SPHK1LMNAGMNNPOLB | |
| Hydrochloric Acid SCHEMBL5053423 | 0.71 | SPHK1 (0.48) | CYP2D6SPHK1LMNAGMNNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995021848-A1 | SPHINGOID BASES AND METHODS FOR THEIR PREPARATION AND USE | THE UNITED STATES OF AMERICA, REPRESENTED BY THE (US) | 1995-08-17 | — | — | WO | disclosed |
| US-5430169-A | Method for preparation of sphingoid bases | THE UNITED STATES OF AMERICA REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1995-07-04 | — | — | US | disclosed |