Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.31 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.31 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GSR | P00390 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL307010 | 0.85 | — | — | |
| SCHEMBL1674752 | 0.85 | GABRR1 (0.33) | GABRR1LMNASLC22A6GRIK1GRIK2 | |
| SCHEMBL9049846 | 0.85 | GRIK1 (0.37) | GABRR1LMNASLC22A6GRIK1GRIK2 | |
| SCHEMBL1079802 | 0.85 | GABRR1 (0.33) | GABRR1LMNASLC22A6GRIK1GRIK2 | |
| SCHEMBL1653844 | 0.84 | SLC22A6 (0.39) | GABRR1LMNASLC22A6GRIK1GRIK2 | |
| SCHEMBL1079794 | 0.83 | GABRR1 (0.32) | GABRR1LMNASLC22A6GRIK1GRIK2 | |
| SCHEMBL4736995 | 0.83 | ALOX15 (0.30) | — | |
| SCHEMBL27578538 | 0.83 | — | — | |
| SCHEMBL1079803 | 0.83 | GABRR1 (0.32) | GABRR1LMNASLC22A6GRIK1GRIK2 | |
| Hydrochloric Acid SCHEMBL11804611 | 0.82 | SLC22A6 (0.38) | GABRR1LMNASLC22A6GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995015770-A1 | PRETARGETING METHODS AND COMPOUNDS | NEORX CORPORATION (US) | 1995-06-15 | — | — | WO | disclosed |
| EP-0083612-A1 | NEW DERIVATIVES OF DIPEPTIDES, METHOD FOR THE PREPARATION THEREOF AND UTILIZATION THEREOF AS DRUGS | FLORK, Michel (FR) | 1983-07-20 | — | — | EP | disclosed |
| WO-1983000146-A1 | NEW DERIVATIVES OF DIPEPTIDES, METHOD FOR THE PREPARATION THEREOF AND UTILIZATION THEREOF AS DRUGS | FLORK, MICHEL | 1983-01-20 | — | — | WO | disclosed |