SCHEMBL4736995

SCHEMBL4736995

NCC(=O)OC(=O)[C@@H](N)CC(N)=O

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL867143 0.85 ALOX15 (0.31) ALOX15BLMPMP22KMT2A
SCHEMBL307010 0.85
SCHEMBL5639011 0.85 ALOX15 (0.35) ALOX15BLMPMP22KMT2A
SCHEMBL11061010 0.84 ALOX15 (0.36) ALOX15BLMPMP22KMT2A
SCHEMBL995487 0.84 ALOX15 (0.36) ALOX15BLMPMP22KMT2A
SCHEMBL9115301 0.83 GABRR1 (0.37)
SCHEMBL5221873 0.80 ALOX15 (0.33) ALOX15BLMPMP22KMT2A
SCHEMBL6239265 0.80 GRIK1 (0.41) ALOX15BLMPMP22KMT2A
SCHEMBL869883 0.80 ALOX15 (0.50) ALOX15BLMPMP22KMT2A
SCHEMBL5187828 0.79 ALOX15 (0.39) ALOX15BLMPMP22KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200056159-A1 NOVEL ADENO-ASSOCIATED VIRUS (AAV) CLADE F VECTOR AND USES THEREFOR THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2020-02-20 US claimed
WO-2008077194-A1 RECEPTOR AGONISTS XENOME LTD (AU) 2008-07-03 WO claimed
CN-1810832-A Dimeric thrombopoietin peptide mimetics binding to MP1 receptor and having thrombopoietic activity AMGEN INC (US) 2006-08-02 CN claimed
CN-1250721-C Mimetic dimeric thrombopoietin peptides that bind to MP1 receptor and have thrombopoietic activity AMGEN INC (US) 2006-04-12 CN claimed
CN-1325447-A Mimetic dimeric thrombopoietin peptides that bind to MP1 receptor and have thrombopoietic activity AMGEN INC (US) 2001-12-05 CN claimed
CN-117430095-A Preparation method of hydroxylamine aqueous solution 浙江锦华新材料股份有限公司 2024-01-23 CN disclosed
EP-3737420-A2 STEROIDS AND ANTIBODY-CONJUGATES THEREOF Regeneron Pharmaceuticals, Inc. (US) 2020-11-18 EP disclosed
US-20200056159-A1 NOVEL ADENO-ASSOCIATED VIRUS (AAV) CLADE F VECTOR AND USES THEREFOR THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2020-02-20 US disclosed
WO-2019136487-A2 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2019-07-11 WO disclosed
CN-109715187-A Insulin glargine and trien (TETA) 艾瑞克有限公司 2019-05-03 CN disclosed
CN-109715186-A Insulin glargine 艾瑞克有限公司 2019-05-03 CN disclosed
US-20150216948-A1 CYTOCHROME P450 SUICIDE GENE SYSTEM HANENBERG HELMUT (US) 2015-08-06 US disclosed
EP-0796335-A1 PRODUCTION OF PEPTIDES USING RECOMBINANT FUSION PROTEIN CONSTRUCTS BIONEBRASKA, INC. (US) 1997-09-24 EP disclosed
CN-1151761-A Subtilisin BPN' variants with reduced adsorption and increased hydrolysis PROCTER & GAMBLE (US) 1997-06-11 CN disclosed
US-5595887-A GENE EXPRESSION, FORMING POLYPEPTIDES FOR PROTEIN PURIFICATION BIONEBRASKA, INC. (US) 1997-01-21 US disclosed
WO-1996017942-A9 PRODUCTION OF PEPTIDES USING RECOMBINANT FUSION PROTEIN CONSTRUCTS 1996-08-15 WO disclosed
WO-1996017942-A1 PRODUCTION OF PEPTIDES USING RECOMBINANT FUSION PROTEIN CONSTRUCTS BIONEBRASKA, INC. (US) 1996-06-13 WO disclosed
EP-0539530-A4 PURIFICATION DIRECTED CLONING OF PEPTIDES. 1993-09-15 EP disclosed
EP-0539530-A1 PURIFICATION DIRECTED CLONING OF PEPTIDES BIONEBRASKA, INC. (US) 1993-05-05 EP disclosed
WO-1992001707-A1 PURIFICATION DIRECTED CLONING OF PEPTIDES BIONEBRASKA, INC. (US) 1992-02-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200056159-A1 NOVEL ADENO-ASSOCIATED VIRUS (AAV) CLADE F VECTOR AND USES THEREFOR VSIG8, ASNS, FARSB ALOX15 2143/4885BLM 3349/4885PMP22 4216/4885
US-20150216948-A1 CYTOCHROME P450 SUICIDE GENE SYSTEM CYP4B1, CYP4A11, CYP2E1 ALOX15 430/4885BLM 4530/4885PMP22 1555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.