SCHEMBL9115336

SCHEMBL9115336

CCOC(=O)c1noc(C2CC2)c1C(=S)c1ccc(Cl)c(Br)c1C

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.34
ALDH1A1 P00352 3/20 0.33
HSP90AA1 P07900 2/20 0.33
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
FTO Q9C0B1 1/20 0.33
DRD2 P14416 1/20 0.33
HTT P42858 1/20 0.33
SMURF2 Q9HAU4 1/20 0.33
SMURF1 Q9HCE7 1/20 0.33
PPARG P37231 1/20 0.33
PPARD Q03181 1/20 0.33
PPARA Q07869 1/20 0.33
KDM4E B2RXH2 2/20 0.32
POLB P06746 1/20 0.32
PKM P14618 1/20 0.32
GPBAR1 Q8TDU6 1/20 0.32
HCRTR2 O43614 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32
MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9115009 0.90 ALDH1A1 (0.34) TSHRALDH1A1HSP90AA1HTTKDM4E
SCHEMBL8492509 0.89 HTT (0.37) TSHRALDH1A1HSP90AA1HTTKDM4E
SCHEMBL9116609 0.89 TSHR (0.34) TSHRALDH1A1HSP90AA1FTOHTT
SCHEMBL8491141 0.82 HTT (0.38) TSHRALDH1A1HSP90AA1HTTKDM4E
SCHEMBL9114974 0.82 PPARG (0.34) SMURF2SMURF1PPARGPPARDPPARA
SCHEMBL9114698 0.81 MAPT (0.37) TSHRALDH1A1PPARGPPARDPPARA
SCHEMBL8816565 0.80 SLC6A4 (0.39) TSHRALDH1A1HSP90AA1FTOHTT
SCHEMBL8490475 0.80 MEN1 (0.37) TSHRALDH1A1HSP90AA1HTTKDM4E
SCHEMBL9113241 0.80 FTO (0.40) FTOHTTPPARGPPARDPPARA
SCHEMBL9115748 0.79 TSHR (0.39) TSHRALDH1A1FTOHTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995022903-A1 NEW PESTICIDAL METHOD RHONE-POULENC AGROCHIMIE (FR) 1995-08-31 WO disclosed