Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.46 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3762091 | 0.87 | ALDH1A1 (0.53) | ALDH1A1MAPK1SMN1; SMN2NPSR1RIPK2 | |
| SCHEMBL30534181 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPK1SMN1; SMN2NPSR1RIPK2 | |
| SCHEMBL13006762 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPK1SMN1; SMN2NPSR1RIPK2 | |
| SCHEMBL11516564 | 0.75 | RIPK2 (0.59) | ALDH1A1MAPK1SMN1; SMN2NPSR1RIPK2 | |
| SCHEMBL2335759 | 0.74 | HSD11B1 (0.62) | ALDH1A1MAPK1SMN1; SMN2NPSR1HSD11B1 | |
| SCHEMBL10077411 | 0.74 | HSD11B1 (0.50) | ALDH1A1MAPK1SMN1; SMN2NPSR1RIPK2 | |
| SCHEMBL23432576 | 0.73 | ALDH1A1 (0.47) | ALDH1A1MAPK1SMN1; SMN2NPSR1RIPK2 | |
| SCHEMBL18876140 | 0.73 | HSD11B1 (0.50) | ALDH1A1MAPK1SMN1; SMN2NPSR1RIPK2 | |
| SCHEMBL14008884 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MAPK1SMN1; SMN2NPSR1RIPK2 | |
| SCHEMBL1013939 | 0.73 | HSD11B1 (0.50) | ALDH1A1MAPK1SMN1; SMN2NPSR1RIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449600-A | Bromo-substituted monomethine thiacyanine dye | FUJI PHOTO FILM CO., LTD. (JP) | 1995-09-12 | — | — | US | disclosed |
| EP-0652472-A1 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1995-05-10 | — | — | EP | disclosed |