SCHEMBL9115541

SCHEMBL9115541

CC[C](OC(C)=O)OC(C)=O

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.56
TSHR P16473 3/20 0.56
TDP1 Q9NUW8 3/20 0.47
LMNA P02545 3/20 0.45
HSD17B10 Q99714 2/20 0.45
FFAR3 O14843 1/20 0.39
SOAT1 P35610 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3204404 0.83 ALDH1A1 (0.39) ALDH1A1TSHRTDP1LMNAHSD17B10
Butane SCHEMBL28203399 0.76 ALDH1A1 (0.71) ALDH1A1TSHRTDP1LMNAHSD17B10
Alcohol SCHEMBL1534284 0.76 ALDH1A1 (0.71) ALDH1A1TSHRTDP1LMNAHSD17B10
Butanone SCHEMBL28280158 0.76 ALDH1A1 (0.71) ALDH1A1TSHRTDP1LMNAHSD17B10
SCHEMBL1331774 0.73
SCHEMBL523 0.73
SCHEMBL1330344 0.73
SCHEMBL9866292 0.73
SCHEMBL1331977 0.73
SCHEMBL5305593 0.73 ALDH1A1 (1.00) ALDH1A1TSHRTDP1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640067-A4 IMPROVED SYNTHESIS OF IOVERSOL. MALLINCKRODT MEDICAL INC (US) 1995-05-31 EP disclosed
EP-0640067-A1 IMPROVED SYNTHESIS OF IOVERSOL. MALLINCKRODT MEDICAL INC (US) 1995-03-01 EP disclosed
WO-1993023365-A1 IMPROVED SYNTHESIS OF IOVERSOL MALLINCKRODT MEDICAL, INC. (US) 1993-11-25 WO disclosed