Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989586 | 0.91 | ELANE (0.34) | ALDH1A1TDP1PRKCAELANE | |
| SCHEMBL9115541 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TSHRHSD17B10TDP1LMNA | |
| SCHEMBL214755 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TSHRHSD17B10TDP1LMNA | |
| SCHEMBL4316110 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TSHRHSD17B10TDP1LMNA | |
| SCHEMBL28018709 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10TDP1GAA | |
| SCHEMBL27905902 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10TDP1GAA | |
| SCHEMBL21831923 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10TDP1GAA | |
| Methyl Alcohol SCHEMBL9630414 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10TDP1GAA | |
| SCHEMBL5780612 | 0.73 | ALDH1A1 (0.45) | ALDH1A1TSHRHSD17B10TDP1GAA | |
| SCHEMBL65267 | 0.71 | ELANE (0.40) | ALDH1A1TSHRPRKCAELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4708955-A | ANTIBACTERIALS | BRISTOL-MYERS COMPANY (US) | 1987-11-24 | — | — | US | claimed |
| US-7683211-B2 | Jasmonate derivative compounds pharmaceutical compounds and methods of use thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2010-03-23 | — | — | US | disclosed |
| US-20080319066-A1 | Jasmonate Derivative Compounds, Pharmaceuticals Compounds and Methods of Use Thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2008-12-25 | — | — | US | disclosed |
| US-20080281105-A1 | Novel Quinolinium Salts and Derivatives | IMMUSOL INCORPORATED (US) | 2008-11-13 | — | — | US | disclosed |
| US-20080274998-A1 | Disaccharide Molecules and Derivatives Thereof and Methods of Using Same | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2008-11-06 | — | — | US | disclosed |
| US-7425651-B2 | Jasmonate derivative compounds, pharmaceuticals compounds and methods of use thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2008-09-16 | — | — | US | disclosed |
| US-20070142474-A1 | Jasmonate derivative compounds, pharmaceuticals compounds and methods of use thereof | VIDAC PHARMA LTD. (IL) | 2007-06-21 | — | — | US | disclosed |
| EP-1689696-A2 | JASMONATE DERIVATIVE COMPOUNDS, PHARMACEUTICALS COMPOSITIONS AND METHODS OF USE THEREOF | Ramot at Tel-Aviv University Ltd. (IL) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005076743-A2 | DISACCHARIDE MOLECULES AND DERIVATIVES THEREOF AND METHODS OF USING SAME | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2005-08-25 | — | — | WO | disclosed |
| WO-2005054172-A2 | JASMONATE DERIVATIVE COMPOUNDS, PHARMACEUTICALS COMPOSITIONS AND METHODS OF USE THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2005-06-16 | — | — | WO | disclosed |
| WO-2001014879-A1 | 4-UNSUBSTITUTED DIHYDROISOQUINOLINONE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-03-01 | — | — | WO | disclosed |
| WO-2001000594-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-01-04 | — | — | WO | disclosed |
| WO-2000045635-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2000-08-10 | — | — | WO | disclosed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | disclosed |
| EP-0863877-A4 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INST (US) | 1999-07-21 | — | — | EP | disclosed |
| EP-0863877-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997016428-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1997-05-09 | — | — | WO | disclosed |
| US-5336768-A | Bactericides | HOFFMANN-LA ROCHE INC. (US) | 1994-08-09 | — | — | US | disclosed |
| EP-0451764-A1 | Carbapenem compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1991-10-16 | — | — | EP | disclosed |
| EP-0409081-A1 | Beta-Lactam Derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274998-A1 | Disaccharide Molecules and Derivatives Thereof and Methods of Using Same | MSN, MAN2B2, MASP2 | ALDH1A1 4079/4885TSHR 2213/4885HSD17B10 4326/4885 |
| US-20070142474-A1 | Jasmonate derivative compounds, pharmaceuticals compounds and methods of use thereof | BCL6, GGPS1, FDPS | ALDH1A1 3349/4885TSHR 4695/4885HSD17B10 588/4885 |
| US-20080281105-A1 | Novel Quinolinium Salts and Derivatives | NQO2, MCL1, KRAS | ALDH1A1 3206/4885TSHR 3448/4885HSD17B10 4176/4885 |
| US-20080319066-A1 | Jasmonate Derivative Compounds, Pharmaceuticals Compounds and Methods of Use Thereof | BCL6, GGPS1, FDPS | ALDH1A1 3349/4885TSHR 4695/4885HSD17B10 588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.