Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9115991 | 0.91 | LTB4R (0.61) | LTB4R | |
| SCHEMBL9333868 | 0.86 | LTB4R (0.58) | LTB4R | |
| SCHEMBL9334165 | 0.82 | LTB4R (0.50) | LTB4R | |
| SCHEMBL9545803 | 0.82 | LTB4R (0.52) | LTB4R | |
| SCHEMBL9333861 | 0.81 | LTB4R (0.69) | LTB4R | |
| SCHEMBL8862019 | 0.81 | LTB4R (0.55) | LTB4R | |
| SCHEMBL8862022 | 0.81 | LTB4R (0.55) | LTB4R | |
| SCHEMBL7030031 | 0.80 | LTB4R (0.55) | LTB4R | |
| SCHEMBL7030035 | 0.80 | LTB4R (0.55) | LTB4R | |
| SCHEMBL8699765 | 0.79 | LTB4R (0.61) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675718-A1 | SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-11 | — | — | EP | disclosed |
| EP-0675718-A4 | SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS LEUKOTRIENE ANTAGONISTS. | SMITHKLINE BEECHAM CORP (US) | 1995-08-22 | — | — | EP | disclosed |
| WO-1994014442-A1 | SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |