Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 20/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333868 | 0.89 | LTB4R (0.58) | LTB4R | |
| SCHEMBL8862085 | 0.88 | LTB4R (0.55) | LTB4R | |
| SCHEMBL9334198 | 0.82 | LTB4R (0.62) | LTB4R | |
| SCHEMBL9115552 | 0.82 | LTB4R (0.49) | LTB4R | |
| SCHEMBL8862022 | 0.80 | LTB4R (0.55) | LTB4R | |
| SCHEMBL8862019 | 0.80 | LTB4R (0.55) | LTB4R | |
| SCHEMBL8862088 | 0.79 | LTB4R (0.65) | LTB4R | |
| SCHEMBL8862070 | 0.79 | LTB4R (0.65) | LTB4R | |
| SCHEMBL7030035 | 0.78 | LTB4R (0.55) | LTB4R | |
| SCHEMBL7030031 | 0.78 | LTB4R (0.55) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593464-A1 | BENZOIC ACID DERIVATIVES and their use as LTB4 inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1994-04-27 | — | — | EP | disclosed |
| EP-0593464-A4 | BENZOIC ACID DERIVATIVES. | SMITHKLINE BEECHAM CORP (US) | 1993-02-12 | — | — | EP | disclosed |
| WO-1991018601-A1 | BENZOIC ACID DERIVATIVES | SMITHKLINE BEECHAM CORPORATION (US) | 1991-12-12 | — | — | WO | disclosed |