Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.36 |
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9116088 | 0.90 | LMNA (0.38) | LMNAGPR84CA2FFAR4FFAR1 | |
| SCHEMBL9150682 | 0.88 | LMNA (0.41) | LMNAGPR84CA2CA1MAPK1 | |
| SCHEMBL9147303 | 0.83 | LMNA (0.44) | LMNAGPR84CA2FFAR4FFAR1 | |
| SCHEMBL9150762 | 0.82 | LMNA (0.40) | LMNAGPR84CA2FFAR4FFAR1 | |
| SCHEMBL9114413 | 0.81 | LMNA (0.39) | LMNAGPR84CA2FFAR4FFAR1 | |
| SCHEMBL2500076 | 0.79 | LMNA (0.40) | LMNAGPR84CA2FFAR4FFAR1 | |
| SCHEMBL2496551 | 0.79 | LMNA (0.40) | LMNAGPR84CA2FFAR4FFAR1 | |
| SCHEMBL2502264 | 0.77 | GPR84 (0.47) | LMNAGPR84FFAR4FFAR1KDM4E | |
| SCHEMBL9116790 | 0.77 | GPR84 (0.47) | LMNAGPR84FFAR4FFAR1KDM4E | |
| SCHEMBL21018932 | 0.77 | GPR84 (0.47) | LMNAGPR84FFAR4FFAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5476671-A | Skin disorders | CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) | 1995-12-19 | — | — | US | disclosed |
| WO-1995016665-A1 | SYNTHETIC CERAMIDES AND THEIR USE IN COSMETIC COMPOSITIONS | UNILEVER PLC (GB) | 1995-06-22 | — | — | WO | disclosed |