Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | WNT3A | P56704 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9115270 | 0.97 | HTR2A (0.52) | HTR2AHTR2CDRD2CYP2D6KDM4E | |
| SCHEMBL9118367 | 0.97 | HTR2A (0.51) | HTR2AHTR2CDRD2CYP2D6KDM4E | |
| SCHEMBL9115669 | 0.97 | HTR2A (0.51) | HTR2AHTR2CDRD2CYP2D6KDM4E | |
| SCHEMBL9116119 | 0.97 | HTR2A (0.51) | HTR2AHTR2CDRD2CYP2D6KDM4E | |
| SCHEMBL9115389 | 0.92 | MAPT (0.45) | MAPTSMN1; SMN2 | |
| SCHEMBL9117021 | 0.91 | KCNH2 (0.48) | HTR2ACYP2D6KDM4ECYP1A2CYP3A4 | |
| SCHEMBL9116840 | 0.89 | KCNH2 (0.45) | HTR2AHTR2CDRD2HTR7 | |
| SCHEMBL9114665 | 0.89 | DRD2 (0.49) | HTR2AHTR2CDRD2CYP2D6KDM4E | |
| SCHEMBL9116078 | 0.86 | HTR2A (0.51) | HTR2AHTR2CDRD2CYP2D6KDM4E | |
| SCHEMBL9118626 | 0.86 | HTR2A (0.50) | HTR2AHTR2CCYP2D6KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995025731-A1 | NOVEL 3-(φ-(4-BENZOYLPIPERIDINO)ALKYL)-4H-BENZOPYRAN-4-ONES, PREPARATION AND THERAPEUTICAL USE THEREOF | PIERRE FABRE MEDICAMENT (FR) | 1995-09-28 | — | — | WO | claimed |