Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | NMT2 | O60551 | 1/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9115885 | 1.00 | DPP7 (0.41) | DPP7DPP8DPP9GSRGNAI3 | |
| SCHEMBL27584151 | 0.89 | NMT2 (0.38) | DPP7DPP8NMT2NMT1MMP2 | |
| SCHEMBL2183030 | 0.89 | NMT2 (0.38) | DPP7DPP8NMT2NMT1MMP2 | |
| SCHEMBL11113882 | 0.86 | DPP8 (0.37) | DPP7DPP8DPP9GSRGNAI3 | |
| SCHEMBL11113886 | 0.86 | DPP8 (0.37) | DPP7DPP8DPP9GSRGNAI3 | |
| SCHEMBL7751947 | 0.85 | DPP7 (0.50) | DPP7DPP8DPP9GSRGNAI3 | |
| SCHEMBL7751944 | 0.85 | DPP7 (0.50) | DPP7DPP8DPP9GSRGNAI3 | |
| SCHEMBL10728100 | 0.84 | DPP8 (0.42) | DPP7DPP8DPP9GSRGNAI3 | |
| SCHEMBL27584132 | 0.82 | GHSR (0.53) | MMP2 | |
| SCHEMBL27584126 | 0.82 | GHSR (0.53) | MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1511044-A | Elogated and multiple spacers in activatible prodrugs | — | 2004-07-07 | — | — | CN | claimed |
| WO-1995016710-A1 | SPECIFIC HYPERIMMUNE ANTI-HIV GLOBULIN FOR PASSIVE IMMUNIZATION | UNITED BIOMEDICAL, INC. (US) | 1995-06-22 | — | — | WO | disclosed |
| EP-0010297-B1 | DERIVATIVES OF POLYENE MACROLIDE ANTIBIOTICS CONTAINING AN AMINO SUGAR MOIETY, PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1983-04-13 | — | — | EP | disclosed |
| US-4272525-A | FUNGICIDES | SCHERING CORPORATION (US) | 1981-06-09 | — | — | US | disclosed |
| EP-0010297-A1 | Derivatives of polyene macrolide antibiotics containing an amino sugar moiety, process for the preparation thereof, and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1980-04-30 | — | — | EP | disclosed |