Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.51 |
| ▸ | CCKBR | P32239 | 11/20 | 0.50 |
| ▸ | CCKAR | P32238 | 7/20 | 0.50 |
| ▸ | BRD4 | O60885 | 4/20 | 0.50 |
| ▸ | BRD2 | P25440 | 4/20 | 0.50 |
| ▸ | BRD3 | Q15059 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1574481 | 0.87 | BRD4 (0.62) | SENP1CCKBRCCKARBRD4BRD2 | |
| SCHEMBL1574479 | 0.87 | BRD4 (0.62) | SENP1CCKBRCCKARBRD4BRD2 | |
| SCHEMBL8711252 | 0.87 | CCKBR (0.65) | SENP1CCKBRCCKAR | |
| SCHEMBL641969 | 0.87 | CCKBR (0.65) | SENP1CCKBRCCKAR | |
| SCHEMBL1574399 | 0.87 | CCKBR (0.65) | SENP1CCKBRCCKAR | |
| Water SCHEMBL9229371 | 0.86 | CCKBR (0.64) | SENP1CCKBRCCKAR | |
| SCHEMBL11961545 | 0.83 | CCKBR (0.52) | SENP1CCKBRCCKARBRD4BRD2 | |
| SCHEMBL644328 | 0.83 | CCKBR (0.62) | CCKBRCCKARBRD4BRD2BRD3 | |
| SCHEMBL1574149 | 0.83 | CCKBR (0.62) | CCKBRCCKARBRD4BRD2BRD3 | |
| SCHEMBL17051633 | 0.82 | SENP1 (0.49) | SENP1CCKBRCCKARBRD4BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995025118-A2 | INHIBITORS OF SH2 DOMAIN INTERACTIONS | TRUSTEES OF TUFTS UNIVERSITY (US) | 1995-09-21 | — | — | WO | disclosed |