SCHEMBL9116243

SCHEMBL9116243

CSc1cc(OCC(F)(F)F)ccc1C(=O)c1cnoc1C1CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
POLB P06746 1/20 0.42
DHODH Q02127 2/20 0.40
CACNA1G O43497 1/20 0.38
CACNA1H O95180 1/20 0.38
CACNA1I Q9P0X4 1/20 0.38
CYP1A2 P05177 3/20 0.36
CYP2C9 P11712 2/20 0.36
EPHX2 P34913 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CNR2 P34972 3/20 0.36
RAB9A P51151 1/20 0.35
MGAT2 Q10469 1/20 0.34
CYP2D6 P10635 2/20 0.34
LMNA P02545 2/20 0.34
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
CACNA1F O60840 1/20 0.34
KCNA5 P22460 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9116248 0.86 ALDH1A1 (0.44) ALDH1A1POLBDHODHCACNA1GCACNA1H
SCHEMBL8494717 0.84 DHODH (0.40) ALDH1A1DHODHEPHX2RAB9ATSHR
SCHEMBL9116510 0.84 KIT (0.39) ALDH1A1DHODHCYP1A2CYP2C9EPHX2
SCHEMBL9113762 0.84 DHODH (0.44) ALDH1A1DHODHEPHX2RAB9ASMN1; SMN2
SCHEMBL29547482 0.83 DHODH (0.49) ALDH1A1DHODHCYP1A2CYP2C9EPHX2
SCHEMBL8489345 0.83 DHODH (0.49) ALDH1A1DHODHCYP1A2CYP2C9EPHX2
SCHEMBL9240645 0.82 ALDH1A1 (0.41) ALDH1A1POLBDHODHCACNA1GCACNA1H
SCHEMBL9115702 0.79 DHODH (0.36) DHODHCNR2
SCHEMBL8888473 0.79 DHODH (0.36) ALDH1A1DHODHEPHX2RAB9ALMNA
SCHEMBL8492364 0.78 HPGD (0.37) ALDH1A1DHODHEPHX2RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995022903-A1 NEW PESTICIDAL METHOD RHONE-POULENC AGROCHIMIE (FR) 1995-08-31 WO disclosed