Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15434645 | 0.72 | NPSR1 (0.48) | NPSR1GAASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL5207542 | 0.69 | ALDH1A1 (0.39) | KDM4EL3MBTL1ALDH1A1MAPT | |
| SCHEMBL11690149 | 0.68 | NPSR1 (0.31) | NPSR1SMN1; SMN2KDM4EGLAALDH1A1 | |
| SCHEMBL11130888 | 0.68 | NPSR1 (0.39) | NPSR1MCL1 | |
| SCHEMBL20508951 | 0.67 | NPSR1 (0.36) | NPSR1L3MBTL1ALDH1A1HPGDMCL1 | |
| SCHEMBL10700385 | 0.65 | KDM4E (0.32) | NPSR1GAASMN1; SMN2KDM4EHTT | |
| SCHEMBL9116008 | 0.64 | — | — | |
| SCHEMBL18120869 | 0.64 | GAA (0.33) | NPSR1GAASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL3856071 | 0.64 | NPSR1 (0.30) | NPSR1 | |
| SCHEMBL2359993 | 0.64 | NPSR1 (0.35) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995011899-A1 | PYRIMIDINE DERIVATIVES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1995-05-04 | — | — | WO | disclosed |