SCHEMBL9116695

SCHEMBL9116695

C=COC(=O)CC.CC(=O)OC=CCc1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
MAOB P27338 1/20 0.37
TOP1 P11387 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
ARG2 P78540 1/20 0.34
MAPT P10636 1/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
PTGS2 P35354 1/20 0.33
ELANE P08246 1/20 0.33
TRPV1 Q8NER1 1/20 0.32
PKM P14618 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TSHR P16473 1/20 0.32
PPARG P37231 1/20 0.32
PPARD Q03181 1/20 0.32
PPARA Q07869 1/20 0.32
CYP3A4 P08684 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4254918 0.85 MAOB (0.50) ALDH1A1MAOBTOP1CA1CA2
SCHEMBL3359392 0.85 MAOB (0.50) ALDH1A1MAOBTOP1CA1CA2
SCHEMBL3359398 0.85 MAOB (0.50) ALDH1A1MAOBTOP1CA1CA2
Styrene SCHEMBL7747013 0.77 ALDH1A1 (0.42) ALDH1A1MAOBMAPTLMNARAB9A
Allylbenzene SCHEMBL28273138 0.76 ALDH1A1 (0.46) ALDH1A1MAOBPTGS2SMN1; SMN2TSHR
SCHEMBL28320915 0.76 ELANE (0.41) ALDH1A1MAPTLMNAELANEPKM
SCHEMBL28249302 0.76 KDM4E (0.33) ALDH1A1MAPTLMNAPTGS2ELANE
SCHEMBL13834343 0.74 MAOB (0.44) ALDH1A1MAOBTOP1CA1CA2
Allylbenzene SCHEMBL28861610 0.74 ALDH1A1 (0.43) ALDH1A1PTGS2SMN1; SMN2TSHRCYP3A4
SCHEMBL5045890 0.74 ALDH1A1 (0.37) ALDH1A1LMNATSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995025090-A1 CYCLIC N-ALKENYLOXYIMIDES AND A METHOD FOR THE PREPARATION OF CYCLIC N-ALKENYLOXYIMIDES, THE CORRESPONDING CYCLIC N-ALKOXYIMIDES AND O-ALKOXYAMINES DSM N.V. (NL) 1995-09-21 WO disclosed