Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TOP1 | P11387 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ARG2 | P78540 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4254918 | 1.00 | MAOB (0.50) | MAOBALDH1A1TOP1CA1CA2 | |
| SCHEMBL3359398 | 1.00 | MAOB (0.50) | MAOBALDH1A1TOP1CA1CA2 | |
| SCHEMBL9116695 | 0.85 | ALDH1A1 (0.37) | MAOBALDH1A1TOP1CA1CA2 | |
| SCHEMBL14775423 | 0.85 | MAOB (0.54) | MAOBALDH1A1TOP1CA1CA2 | |
| SCHEMBL13834343 | 0.83 | MAOB (0.44) | MAOBALDH1A1TOP1CA1CA2 | |
| SCHEMBL3247823 | 0.81 | ALDH1A1 (0.52) | MAOBALDH1A1TOP1CA1CA2 | |
| SCHEMBL6551301 | 0.80 | TDP1 (0.50) | MAOBALDH1A1TOP1CA1CA2 | |
| SCHEMBL29273747 | 0.80 | LMNA (0.47) | MAOBALDH1A1TOP1CA1CA2 | |
| SCHEMBL13899906 | 0.78 | RAB9A (0.38) | ALDH1A1CA1CA2LMNATSHR | |
| SCHEMBL11267329 | 0.77 | MAOB (0.45) | MAOBALDH1A1TOP1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004091307-A2 | FEED ADDITIVES AGAINST DISEASSE INFECTION IN TERRESTRIAL AND AQUATIC ANIMALS | ADVANCED BIONUTRITON CORPORATION (US) | 2004-10-28 | — | — | WO | claimed |
| US-20150073045-A1 | POLYCYCLIC COMPOUNDS AND METHODS RELATED THERETO | CORNELL UNIVERSITY (US) | 2015-03-12 | — | — | US | disclosed |
| US-20140128458-A1 | POLYCYCLIC COMPOUNDS AND METHODS RELATED THERETO | CORNELL UNIVERSITY (US) | 2014-05-08 | — | — | US | disclosed |
| US-8563603-B2 | Polycyclic compounds and methods related thereto | CORNELL UNIVERSITY (US) | 2013-10-22 | — | — | US | disclosed |
| US-20120225053-A1 | COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF CONDITIONS ASSOCIATED WITH INFLAMATION | DUSHENKOV SLAVIK (US) | 2012-09-06 | — | — | US | disclosed |
| WO-2010048452-A2 | POLYCYCLIC COMPOUNDS AND METHODS RELATED THERETO | CHAVEZ KATHRYN JILL (US) | 2010-04-29 | — | — | WO | disclosed |
| US-7638114-B1 | Method for disinfecting the air | SCHUER JOERG PETER | 2009-12-29 | — | — | US | disclosed |
| US-7351739-B2 | Bioactive compounds and methods of uses thereof | WELLGEN, INC. (US) | 2008-04-01 | — | — | US | disclosed |
| US-20080045587-A1 | PLANT PROTECTION | SCHUR JORG P | 2008-02-21 | — | — | US | disclosed |
| EP-1883416-A2 | COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF CONDITIONS ASSOCIATED WITH INFLAMMATION | Wellgen, Inc. (US) | 2008-02-06 | — | — | EP | disclosed |
| US-20020176882-A1 | Additive the improvement and/or stabilization of the keeping quality of microbially perishable products | SCHUR JORG PETER (DE) | 2002-11-28 | — | — | US | disclosed |
| EP-0415745-B1 | Process for producing alpha-beta-unsaturated carbonyl compound | NIPPON ZEON CO (JP) | 1994-08-03 | — | — | EP | disclosed |
| EP-0404497-B1 | A process for producing an alpha,beta-unsaturated carbonyl compound | NIPPON ZEON CO (JP) | 1994-06-01 | — | — | EP | disclosed |
| EP-0428343-B1 | A process for producing an alpha,beta-unsaturated carbonyl compound | NIPPON ZEON CO (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-5118862-A | Process for producing αβ-unsaturated carbonyl compound | NIPPON ZEON CO., LTD. (JP) | 1992-06-02 | — | — | US | disclosed |
| US-5118863-A | Process for producing an α,β-unsaturated carbonyl compound | NIPPON ZEON CO., LTD. (JP) | 1992-06-02 | — | — | US | disclosed |
| EP-0415745-A2 | Process for producing alpha-beta-unsaturated carbonyl compound | NIPPON ZEON CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |
| EP-0404497-A2 | A process for producing an alpha,beta-unsaturated carbonyl compound | NIPPON ZEON CO., LTD. (JP) | 1990-12-27 | — | — | EP | disclosed |
| US-4952690-A | 6-substituted thia-aza compounds | CIBA-GEIGY CORPORATION (US) | 1990-08-28 | — | — | US | disclosed |
| US-4692442-A | ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1987-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150073045-A1 | POLYCYCLIC COMPOUNDS AND METHODS RELATED THERETO | PKD1, THPO, CCNO | MAOB 3103/4885ALDH1A1 1263/4885TOP1 1149/4885 |
| US-20140128458-A1 | POLYCYCLIC COMPOUNDS AND METHODS RELATED THERETO | PKD1, THPO, CCNO | MAOB 3103/4885ALDH1A1 1263/4885TOP1 1149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.