Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9559137 | 0.99 | LMNA (0.54) | LMNAMAPTKMT2AL3MBTL1MEN1 | |
| SCHEMBL8658226 | 0.90 | MAPT (0.55) | LMNAMAPTKMT2AL3MBTL1MEN1 | |
| Hydrochloric Acid SCHEMBL5630497 | 0.84 | KMT2A (0.52) | LMNAMAPTKMT2AMEN1KDM4E | |
| SCHEMBL9118166 | 0.81 | MAPT (0.56) | LMNAMAPTKMT2AL3MBTL1MEN1 | |
| SCHEMBL9119813 | 0.80 | CHRNA7 (0.53) | MAPTKMT2AL3MBTL1MEN1KDM4E | |
| SCHEMBL9119799 | 0.79 | EPAS1 (0.57) | LMNAMAPTKMT2AMEN1KDM4E | |
| Hydrochloric Acid SCHEMBL9119630 | 0.78 | CHRNA7 (0.52) | MAPTKMT2AL3MBTL1MEN1KDM4E | |
| SCHEMBL23565733 | 0.78 | KMT2A (0.61) | LMNAKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL9119816 | 0.77 | KMT2A (0.54) | LMNAMAPTKMT2AL3MBTL1MEN1 | |
| SCHEMBL14113135 | 0.76 | TMPRSS4 (0.53) | MAPTKDM4EALDH1A1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477819-B1 | Benzimidazole derivatives, their preparation and use | NEUROSEARCH AS (DK) | 1995-03-15 | — | — | EP | disclosed |
| US-5200422-A | Benzimidazole derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1993-04-06 | — | — | US | disclosed |
| EP-0477819-A2 | Benzimidazole derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1992-04-01 | — | — | EP | disclosed |