Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | KIF11 | P52732 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658226 | 0.87 | MAPT (0.55) | MAPTKDM4EL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL9116795 | 0.81 | LMNA (0.55) | MAPTKDM4EL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL9121209 | 0.81 | MAPK1 (0.52) | MAPTALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL9118789 | 0.80 | ACLY (0.47) | MAPTKDM4EL3MBTL1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL9559137 | 0.80 | LMNA (0.54) | MAPTKDM4EL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL6141350 | 0.72 | CFTR (0.64) | MAPTKDM4EL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL9121222 | 0.72 | MAPK1 (0.53) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL330883 | 0.72 | L3MBTL1 (0.70) | MAPTKDM4EL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL19507651 | 0.71 | MAPK8 (0.39) | MAPTKDM4EL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL4459254 | 0.71 | KDM4E (0.59) | MAPTKDM4EL3MBTL1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477819-B1 | Benzimidazole derivatives, their preparation and use | NEUROSEARCH AS (DK) | 1995-03-15 | — | — | EP | disclosed |
| US-5200422-A | Benzimidazole derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1993-04-06 | — | — | US | disclosed |
| EP-0477819-A2 | Benzimidazole derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1992-04-01 | — | — | EP | disclosed |