Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9283073 | 0.88 | KDM4E (0.40) | AKR1B1SLC22A12PTGS2KMT2AMEN1 | |
| SCHEMBL3044981 | 0.82 | AKR1B1 (0.74) | AKR1B1P2RX7SLC22A12PTGS2ADRA2A | |
| SCHEMBL8278400 | 0.79 | AKR1B1 (0.52) | AKR1B1P2RX7SLC22A12PTGS2ADRA2A | |
| SCHEMBL7674948 | 0.79 | AKR1B1 (0.52) | AKR1B1P2RX7SLC22A12PTGS2ADRA2A | |
| SCHEMBL9335830 | 0.78 | KDM4E (0.34) | SLC22A12PTGS2KMT2AMEN1LMNA | |
| SCHEMBL2373994 | 0.75 | SMN1; SMN2 (0.51) | AKR1B1P2RX7KMT2AMAPK1 | |
| SCHEMBL2722418 | 0.74 | AKR1B1 (0.45) | AKR1B1P2RX7SLC22A12PTGS2ADRA2A | |
| SCHEMBL31514215 | 0.73 | NLRP3 (0.54) | AKR1B1KMT2AMEN1LMNACYP3A4 | |
| SCHEMBL13185285 | 0.73 | AKR1B1 (0.46) | AKR1B1P2RX7SLC22A12PTGS2ADRA2A | |
| SCHEMBL11389910 | 0.72 | CTBP2 (0.44) | AKR1B1P2RX7PTGS2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395721-A | Electrophotographic material for color proofing | FUJI PHOTO FILM CO., LTD. (JP) | 1995-03-07 | — | — | US | disclosed |
| US-5178982-A | Binder resin is a blend of graft polymers | FUJI PHOTO FILM CO., LTD. (JP) | 1993-01-12 | — | — | US | disclosed |
| US-5116710-A | Multilayer photoconductive layer with photoconductive compound and resin binder | FUJI PHOTO FILM CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |