Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31186400 | 0.71 | PTPN1 (0.37) | OPRM1OPRD1OPRK1OPRL1ESR1 | |
| SCHEMBL31186294 | 0.71 | PTPN1 (0.37) | OPRM1OPRD1OPRK1OPRL1ESR1 | |
| SCHEMBL31186272 | 0.71 | PTPN1 (0.37) | OPRM1OPRD1OPRK1OPRL1ESR1 | |
| SCHEMBL8214420 | 0.69 | MAOA (0.36) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL14778089 | 0.65 | MMP2 (0.48) | MMP2MMP9MMP8MMP13CSNK1E | |
| SCHEMBL14777669 | 0.65 | MMP2 (0.48) | MMP2MMP9MMP8MMP13CSNK1E | |
| SCHEMBL14779091 | 0.65 | MMP2 (0.48) | MMP2MMP9MMP8MMP13CSNK1E | |
| SCHEMBL14779337 | 0.65 | MMP2 (0.48) | MMP2MMP9MMP8MMP13CSNK1E | |
| SCHEMBL14779793 | 0.65 | MMP2 (0.48) | MMP2MMP9MMP8MMP13CSNK1E | |
| SCHEMBL14779509 | 0.64 | MMP2 (0.50) | MMP2MMP9MMP8MMP13CSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995014012-A1 | 5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE, DAVIS & COMPANY (US) | 1995-05-26 | — | — | WO | disclosed |