Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 13/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | CCR2 | P41597 | 3/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1881 | 0.78 | KCNH2 (0.65) | SLC6A4SLC6A3SLC6A2OPRL1OPRM1 | |
| Hydrochloric Acid SCHEMBL11107752 | 0.76 | SLC6A4 (0.54) | SLC6A4SLC6A3SLC6A2OPRK1 | |
| SCHEMBL20459111 | 0.72 | SLC6A3 (0.60) | SLC6A4SLC6A3SLC6A2OPRL1OPRM1 | |
| Hydrochloric Acid SCHEMBL10561926 | 0.70 | SLC6A4 (0.52) | SLC6A4SLC6A3SLC6A2OPRL1OPRM1 | |
| SCHEMBL11109361 | 0.69 | SLC6A4 (0.61) | SLC6A4SLC6A3SLC6A2 | |
| Hydrochloric Acid SCHEMBL11104053 | 0.67 | SLC6A3 (0.62) | SLC6A4SLC6A3SLC6A2 | |
| Hydrochloric Acid SCHEMBL5433219 | 0.67 | SLC6A3 (0.60) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3519163 | 0.64 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL15133746 | 0.64 | CCR2 (0.46) | SLC6A4SLC6A3SLC6A2OPRL1OPRM1 | |
| SCHEMBL5087133 | 0.64 | SLC6A3 (0.63) | SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995021615-A1 | USE OF ARYLCYCLOBUTYLALKYLAMINES FOR THE TREATMENT OF SEIZURES AND NEUROLOGICAL DISORDERS | KNOLL AG (DE) | 1995-08-17 | — | — | WO | claimed |
| WO-1995021615-A1 | USE OF ARYLCYCLOBUTYLALKYLAMINES FOR THE TREATMENT OF SEIZURES AND NEUROLOGICAL DISORDERS | KNOLL AG (DE) | 1995-08-17 | — | — | WO | disclosed |