Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9115001 | 0.93 | MAOB (0.56) | MAOBMAOAFFAR1MEN1POLB | |
| SCHEMBL9116311 | 0.85 | MAOB (0.46) | MAOBAPPMAOAMEN1POLB | |
| SCHEMBL9116935 | 0.79 | MAOB (0.53) | MAOBAPPMAOANR4A2FOXM1 | |
| SCHEMBL15132940 | 0.78 | RXRA (0.64) | MAOBAPPMAOAFFAR1MEN1 | |
| SCHEMBL10722524 | 0.78 | RXRA (0.64) | MAOBAPPMAOAFFAR1MEN1 | |
| SCHEMBL9116702 | 0.77 | CARM1 (0.46) | MAOBMEN1POLBKMT2ANPSR1 | |
| SCHEMBL11000264 | 0.74 | MAOB (0.58) | MAOBAPPMAOAFFAR1MEN1 | |
| Hydrochloric Acid SCHEMBL9734295 | 0.74 | MAOB (0.57) | MAOBAPPMAOAMEN1POLB | |
| SCHEMBL14461695 | 0.73 | MAOB (0.56) | MAOBAPPMAOAFFAR1MEN1 | |
| SCHEMBL10991891 | 0.72 | MAOB (0.80) | MAOBAPPMAOAKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0666840-A1 | BENZYLAMINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-08-16 | — | — | EP | disclosed |
| WO-1995006630-A1 | BENZYLAMINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-09 | — | — | WO | disclosed |