Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.44 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPD | P32754 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9117429 | 0.85 | MAOB (0.50) | MAOBMAOANR4A2MEN1MAPK1 | |
| Oxalic Acid SCHEMBL9115001 | 0.79 | MAOB (0.56) | MAOBMAOANR4A2MEN1MAPK1 | |
| SCHEMBL9115916 | 0.78 | MAOB (0.50) | MAOBMAOASPHK1NR4A2SPHK2 | |
| SCHEMBL9116702 | 0.76 | CARM1 (0.46) | MAOBMEN1KMT2APOLBNPSR1 | |
| SCHEMBL3418111 | 0.72 | BCHE (0.56) | MAOBMEN1KMT2ASMN1; SMN2ALOX5 | |
| SCHEMBL13138365 | 0.71 | MAOA (0.48) | MAOBMAOANR4A2ACACAMEN1 | |
| SCHEMBL8985602 | 0.70 | MEN1 (0.48) | MAOBMAOASPHK1NR4A2SPHK2 | |
| Hydrochloric Acid SCHEMBL8985560 | 0.70 | MEN1 (0.48) | MAOBMAOASPHK1NR4A2SPHK2 | |
| SCHEMBL9116935 | 0.70 | MAOB (0.53) | MAOBMAOANR4A2APP | |
| SCHEMBL18745406 | 0.69 | MAOB (0.52) | MAOBMAOANR4A2ACACAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0666840-A1 | BENZYLAMINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-08-16 | — | — | EP | disclosed |
| WO-1995006630-A1 | BENZYLAMINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-09 | — | — | WO | disclosed |