SCHEMBL9117745

SCHEMBL9117745

CCCCCCCCCCCCOc1ccc(CCC(=O)OC)cc1C(=O)NCCCCCCNC(=O)OC(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.45
NPSR1 Q6W5P4 1/20 0.44
PTPN1 P18031 1/20 0.43
CNR2 P34972 3/20 0.43
CA12 O43570 3/20 0.42
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CA9 Q16790 3/20 0.42
SMPD1 P17405 1/20 0.42
SUCNR1 Q9BXA5 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9119461 0.91 PTPN1 (0.46) ALDH1A1NPSR1PTPN1CNR2CA12
SCHEMBL8369255 0.87 ALDH1A1 (0.47) ALDH1A1NPSR1CNR2SMPD1
Hydrochloric Acid SCHEMBL9118183 0.86 ALDH1A1 (0.47) ALDH1A1NPSR1CNR2SMPD1
SCHEMBL9117658 0.82 ALDH1A1 (0.47) ALDH1A1NPSR1CA12CA1CA2
SCHEMBL9116566 0.81 ALDH1A1 (0.45) ALDH1A1NPSR1CA12CA1CA2
SCHEMBL9236586 0.80 PTPN11 (0.53) ALDH1A1NPSR1PTPN1SUCNR1
SCHEMBL9116472 0.80 ALDH1A1 (0.65) ALDH1A1NPSR1CNR2CA12CA1
SCHEMBL9117701 0.79 CA12 (0.45) ALDH1A1NPSR1CA12CA1CA2
SCHEMBL8516215 0.78 ALDH1A1 (0.49) ALDH1A1NPSR1PTPN1CNR2CA12
SCHEMBL8516580 0.77 CNR2 (0.49) ALDH1A1NPSR1PTPN1CNR2SMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995017888-A1 PHENYLMETHYL HEXANAMIDES, AND THE USE THEREOF SMITHKLINE BEECHAM CORPORATION (US) 1995-07-06 WO disclosed