Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 4/20 | 0.39 |
| ▸ | F3 | P13726 | 4/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 3/20 | 0.37 |
| ▸ | ACE | P12821 | 3/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9105107 | 0.89 | GHSR (0.42) | NPSR1GAAALDH1A1XIAPF7 | |
| SCHEMBL9105116 | 0.89 | GHSR (0.42) | NPSR1GAAALDH1A1XIAPF7 | |
| SCHEMBL9119997 | 0.86 | XIAP (0.45) | NPSR1ALDH1A1XIAPF7F3 | |
| SCHEMBL9105221 | 0.85 | GHSR (0.42) | XIAPF7F3F2MME | |
| SCHEMBL9105226 | 0.85 | GHSR (0.42) | XIAPF7F3F2MME | |
| SCHEMBL9117870 | 0.82 | F7 (0.38) | ALDH1A1XIAPF7F3F2 | |
| SCHEMBL9119359 | 0.81 | NPSR1 (0.42) | NPSR1GAAALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL9104983 | 0.81 | GHSR (0.47) | XIAPF7F3F2POLB | |
| SCHEMBL9105564 | 0.80 | GHSR (0.54) | XIAPF7F3F2MME | |
| SCHEMBL9109384 | 0.80 | GHSR (0.40) | XIAPF7F3F2MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003290-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-02-02 | — | — | WO | disclosed |