Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9117727 | 0.89 | LTB4R (0.52) | LTB4RLTB4R2PLA2G4B | |
| Hydrochloric Acid SCHEMBL8994941 | 0.88 | LTB4R (0.51) | LTB4RLTB4R2PLA2G4BPRSS1 | |
| Hydrochloric Acid SCHEMBL8994889 | 0.85 | LMNA (0.47) | PLA2G4BPRSS1SMPD1THRATHRB | |
| Hydrochloric Acid SCHEMBL8994904 | 0.85 | LTB4R (0.43) | LTB4RLTB4R2PLA2G4BPRSS1SMPD1 | |
| SCHEMBL7711975 | 0.84 | LTB4R (0.72) | LTB4RLTB4R2PLA2G4BPRSS1THRA | |
| SCHEMBL9119999 | 0.83 | LTB4R (0.46) | LTB4RLTB4R2KMT2A | |
| SCHEMBL7711188 | 0.83 | MAOB (0.48) | LTB4RLTB4R2 | |
| Hydrochloric Acid SCHEMBL8995021 | 0.83 | LTB4R (0.68) | LTB4RLTB4R2PLA2G4BPRSS1SMPD1 | |
| Hydrochloric Acid SCHEMBL8994877 | 0.83 | LTB4R (0.55) | LTB4RLTB4R2THRATHRBKMT2A | |
| Hydrochloric Acid SCHEMBL8994965 | 0.83 | LTB4R (0.55) | LTB4RLTB4R2THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518819-B1 | Amidino compounds, their manufacture and use as medicament | CIBA GEIGY AG (CH) | 1995-08-02 | — | — | EP | claimed |
| EP-0518819-A2 | Amidino compounds, their manufacture and use as medicament | CIBA-GEIGY AG (CH) | 1992-12-16 | — | — | EP | claimed |