Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | F7 | P08709 | 1/20 | 0.63 |
| ▸ | F3 | P13726 | 1/20 | 0.63 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.63 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.63 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.63 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.63 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.63 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.63 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.63 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.62 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ALPL | P05186 | 1/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2000041 | 0.88 | HDAC1 (0.74) | HDAC1HDAC6LMNAHIF1AF7 | |
| SCHEMBL27793474 | 0.86 | ALDH1A1 (0.62) | HDAC1HDAC6LMNAHIF1AF7 | |
| SCHEMBL27714168 | 0.86 | HDAC1 (0.61) | HDAC1HDAC6LMNAHIF1AF7 | |
| SCHEMBL18136526 | 0.85 | HDAC1 (0.65) | HDAC1HDAC6LMNAHIF1AF7 | |
| SCHEMBL5793445 | 0.83 | HDAC1 (0.67) | HDAC1HDAC6LMNAHIF1AROCK2 | |
| SCHEMBL29011921 | 0.83 | GAA (0.71) | HDAC1HDAC6LMNAHIF1AROCK2 | |
| SCHEMBL10896472 | 0.83 | HDAC1 (0.57) | HDAC1HDAC6LMNAHIF1AF7 | |
| SCHEMBL10894701 | 0.83 | HTT (0.58) | HDAC1HDAC6LMNAHIF1AF7 | |
| SCHEMBL28702894 | 0.82 | HDAC1 (0.56) | HDAC1HDAC6LMNAHIF1AF7 | |
| SCHEMBL2488253 | 0.81 | HDAC1 (0.65) | HDAC1HDAC6LMNAHIF1AROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114656402-B | Fluorine-containing nicotinoyl urea compound and application thereof | 青岛科技大学 | 2024-01-30 | — | — | CN | claimed |
| CN-114656402-A | Fluorine-containing nicotinoyl urea compound and application thereof | 青岛科技大学 | 2022-06-24 | — | — | CN | claimed |
| CN-108697081-B | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 美国陶氏益农公司 | 2021-07-23 | — | — | CN | claimed |
| CN-112176368-B | Potassium chloride acidic zinc plating electroplating solution and application thereof | 武汉奥邦表面技术有限公司 | 2021-07-09 | — | — | CN | claimed |
| CN-112176368-A | Potassium chloride acidic zinc plating electroplating solution and application thereof | 武汉奥邦表面技术有限公司 | 2021-01-05 | — | — | CN | claimed |
| CN-1251523-A | Sulfonamide derivatives | LILLY CO ELI (US) | 2000-04-26 | — | — | CN | claimed |
| CN-114656402-B | Fluorine-containing nicotinoyl urea compound and application thereof | 青岛科技大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-114656402-B | Fluorine-containing nicotinoyl urea compound and application thereof | 青岛科技大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-114656402-B | Fluorine-containing nicotinoyl urea compound and application thereof | 青岛科技大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-114656402-A | Fluorine-containing nicotinoyl urea compound and application thereof | 青岛科技大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-114656402-A | Fluorine-containing nicotinoyl urea compound and application thereof | 青岛科技大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-114656402-A | Fluorine-containing nicotinoyl urea compound and application thereof | 青岛科技大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-112176368-B | Potassium chloride acidic zinc plating electroplating solution and application thereof | 武汉奥邦表面技术有限公司 | 2021-07-09 | — | — | CN | disclosed |
| CN-1205686-A | Aryl benzoyl urea derivative and pesticidal compsn. comprising same | HANWHA CORP (KR) | 1999-01-20 | — | — | CN | disclosed |
| WO-1995033711-A1 | PHENYL BENZOYL(NICOTINOYL) UREA DERIVATIVES | HANWHA CORPORATION (KR) | 1995-12-14 | — | — | WO | disclosed |
| EP-0007648-B1 | NEW ACYLUREAS WITH PHARMACEUTICAL ACTIVITY, THE PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS WHICH CONTAIN THEM | Investigacion Tecnica Y Aplicada, S.A. (ES) | 1982-08-11 | — | — | EP | disclosed |
| EP-0004187-B1 | HETEROCYCLYLCARBONYL DERIVATIVES OF UREA AND THEIR USE AS AGENTS FOR DISSOLUTION OF GALLSTONES | PFIZER INC. (US) | 1982-03-17 | — | — | EP | disclosed |
| US-4252957-A | GALLSTONE SOLVENTS | PFIZER INC. (US) | 1981-02-24 | — | — | US | disclosed |
| EP-0004187-A1 | Heterocyclylcarbonyl derivatives of urea and their use as agents for dissolution of gallstones | PFIZER INC. (US) | 1979-09-19 | — | — | EP | disclosed |
| US-4163784-A | ACYLUREA DERIVATIVES | PFIZER INC. (US) | 1979-08-07 | — | — | US | disclosed |