Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 3/20 | 0.48 |
| ▸ | HTR7 | P34969 | 3/20 | 0.48 |
| ▸ | HTR6 | P50406 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9289676 | 0.97 | KDM4E (0.53) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9115603 | 0.93 | HTR2A (0.57) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9115113 | 0.90 | HTR2A (0.53) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9117274 | 0.88 | ALDH1A1 (0.54) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9117523 | 0.88 | HTR2A (0.50) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9115981 | 0.86 | HTR2A (0.50) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9115963 | 0.86 | HTR2A (0.50) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9115835 | 0.86 | HTR2A (0.50) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9116097 | 0.86 | ALDH1A1 (0.51) | HTR2AKDM4EALDH1A1HTR2C | |
| SCHEMBL9116862 | 0.86 | HTR2C (0.57) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995025731-A1 | NOVEL 3-(φ-(4-BENZOYLPIPERIDINO)ALKYL)-4H-BENZOPYRAN-4-ONES, PREPARATION AND THERAPEUTICAL USE THEREOF | PIERRE FABRE MEDICAMENT (FR) | 1995-09-28 | — | — | WO | claimed |
| WO-1995025731-A1 | NOVEL 3-(φ-(4-BENZOYLPIPERIDINO)ALKYL)-4H-BENZOPYRAN-4-ONES, PREPARATION AND THERAPEUTICAL USE THEREOF | PIERRE FABRE MEDICAMENT (FR) | 1995-09-28 | — | — | WO | disclosed |