Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9289676 | 0.89 | KDM4E (0.53) | ALDH1A1KDM4EHSD17B10HTR2AHTR2C | |
| SCHEMBL9118514 | 0.86 | HTR2A (0.53) | ALDH1A1KDM4EHTR2AHTR2C | |
| SCHEMBL9116840 | 0.85 | KCNH2 (0.45) | KCNH2DRD2CHRM2CHRM4CHRM5 | |
| SCHEMBL9117274 | 0.83 | ALDH1A1 (0.54) | ALDH1A1KDM4EKCNH2HSD17B10MEN1 | |
| SCHEMBL9117345 | 0.83 | CHRM2 (0.49) | ALDH1A1KDM4EKCNH2CHRM2CHRM4 | |
| SCHEMBL9115603 | 0.81 | HTR2A (0.57) | KDM4EHTR2AHTR2C | |
| SCHEMBL9117523 | 0.79 | HTR2A (0.50) | KDM4EHTR2AHTR2C | |
| SCHEMBL9116862 | 0.77 | HTR2C (0.57) | KDM4EDRD2MEN1KMT2AHTR2A | |
| SCHEMBL9114665 | 0.76 | DRD2 (0.49) | ALDH1A1KDM4EDRD2HTR2AHTR2C | |
| SCHEMBL9115113 | 0.76 | HTR2A (0.53) | ALDH1A1KDM4EKCNH2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995025731-A1 | NOVEL 3-(φ-(4-BENZOYLPIPERIDINO)ALKYL)-4H-BENZOPYRAN-4-ONES, PREPARATION AND THERAPEUTICAL USE THEREOF | PIERRE FABRE MEDICAMENT (FR) | 1995-09-28 | — | — | WO | claimed |
| WO-1995025731-A1 | NOVEL 3-(φ-(4-BENZOYLPIPERIDINO)ALKYL)-4H-BENZOPYRAN-4-ONES, PREPARATION AND THERAPEUTICAL USE THEREOF | PIERRE FABRE MEDICAMENT (FR) | 1995-09-28 | — | — | WO | disclosed |