Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 17/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 17/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2242 | 0.99 | SLC6A4 (0.60) | SLC6A4SLC6A3SLC6A2TP53CYP3A4 | |
| SCHEMBL10840419 | 0.87 | SLC6A4 (0.78) | SLC6A4SLC6A3SLC6A2TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL2409 | 0.86 | SLC6A4 (0.76) | SLC6A4SLC6A3SLC6A2TP53CYP3A4 | |
| SCHEMBL10837947 | 0.82 | SLC6A4 (0.62) | SLC6A4SLC6A3SLC6A2TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL2253 | 0.81 | SLC6A4 (0.61) | SLC6A4SLC6A3SLC6A2TP53CYP3A4 | |
| SCHEMBL10550753 | 0.80 | SLC6A4 (0.71) | SLC6A4SLC6A3SLC6A2TP53CYP3A4 | |
| SCHEMBL2190 | 0.79 | SLC6A3 (0.46) | SLC6A4SLC6A3SLC6A2 | |
| Hydrochloric Acid SCHEMBL2283 | 0.79 | SLC6A4 (0.69) | SLC6A4SLC6A3SLC6A2TP53CYP3A4 | |
| SCHEMBL2102 | 0.78 | SLC6A4 (0.54) | SLC6A4SLC6A3SLC6A2TP53CYP3A4 | |
| SCHEMBL2316 | 0.76 | SLC6A4 (0.43) | SLC6A4SLC6A3SLC6A2TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995021615-A1 | USE OF ARYLCYCLOBUTYLALKYLAMINES FOR THE TREATMENT OF SEIZURES AND NEUROLOGICAL DISORDERS | KNOLL AG (DE) | 1995-08-17 | — | — | WO | claimed |
| WO-1995021615-A1 | USE OF ARYLCYCLOBUTYLALKYLAMINES FOR THE TREATMENT OF SEIZURES AND NEUROLOGICAL DISORDERS | KNOLL AG (DE) | 1995-08-17 | — | — | WO | disclosed |