Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CCR6 | P51684 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | PPOX | P50336 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | ESRRA | P11474 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1365207 | 0.85 | MAPT (0.71) | MAPTTDP1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10791384 | 0.84 | TDP1 (0.63) | MAPTTDP1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL1367400 | 0.83 | MAPT (0.56) | MAPTTDP1LMNAALDH1A1NPSR1 | |
| SCHEMBL9119989 | 0.82 | CFTR (0.64) | MAPTLMNAALDH1A1NPSR1HPGD | |
| SCHEMBL5739859 | 0.82 | L3MBTL1 (0.56) | MAPTTDP1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL21332706 | 0.81 | MAPT (0.57) | MAPTTDP1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL1450704 | 0.81 | CFTR (0.60) | MAPTTDP1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL30959714 | 0.81 | CFTR (0.60) | MAPTTDP1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL31719692 | 0.79 | PARP14 (0.61) | MAPTTDP1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8077154 | 0.79 | MAPT (0.54) | MAPTTDP1LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995033460-A1 | ANTI-INFLAMMATORY COUMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-12-14 | — | — | WO | disclosed |
| US-5447957-A | Anti-inflammatory compounds | SMITHKLINE BEECHAM CORP. (US) | 1995-09-05 | — | — | US | disclosed |