Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.48 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9118243 | 0.89 | L3MBTL1 (0.64) | CFTRL3MBTL1RAB9AMAPTNPSR1 | |
| SCHEMBL8076970 | 0.84 | L3MBTL1 (0.52) | CFTRL3MBTL1RAB9AMAPTNPSR1 | |
| SCHEMBL1365182 | 0.84 | CFTR (0.64) | CFTRL3MBTL1RAB9AMAPTNPSR1 | |
| SCHEMBL9118601 | 0.82 | MAPT (0.53) | CFTRMAPTNPSR1LMNAALDH1A1 | |
| SCHEMBL1364802 | 0.81 | CFTR (0.64) | CFTRL3MBTL1RAB9AMAPTNPSR1 | |
| Diphenylmethanol SCHEMBL8076973 | 0.81 | L3MBTL1 (0.53) | CFTRL3MBTL1RAB9AMAPTNPSR1 | |
| SCHEMBL5739338 | 0.80 | ALDH1A1 (0.51) | CFTRRAB9AMAPTNPSR1LMNA | |
| SCHEMBL30660552 | 0.79 | CFTR (1.00) | CFTRL3MBTL1RAB9AMAPTATM | |
| SCHEMBL1451351 | 0.79 | CFTR (1.00) | CFTRL3MBTL1RAB9AMAPTATM | |
| SCHEMBL2978238 | 0.78 | L3MBTL1 (1.00) | CFTRL3MBTL1RAB9AMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995033460-A1 | ANTI-INFLAMMATORY COUMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-12-14 | — | — | WO | disclosed |
| US-5447957-A | Anti-inflammatory compounds | SMITHKLINE BEECHAM CORP. (US) | 1995-09-05 | — | — | US | disclosed |